2.3.1.291: sphingoid base N-palmitoyltransferase
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Reaction
Synonyms
CerS4, CerS5, LASS5, longevity assurance homolog 5, mammalian ceramide synthase 5
ECTree
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Source Tissue
Source Tissue on EC 2.3.1.291 - sphingoid base N-palmitoyltransferase
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CerS5 mRNA is detected in most cells within gray and white matter of all brain regions
LASS5 is the predominant ceramide synthase isoform detected in lung epithelia
an age-dependent decline of both isoforms CerS1 and CerS5 mRNA expression is observed in skeletal muscle biopsies
the expression of CerS1 and CerS5 mRNA, encoding the ceramide synthases with substrate preference for C16:0 and C18:0 acyl chains, respectively, is downregulated in skeletal muscle of aged mice