2.3.1.291: sphingoid base N-palmitoyltransferase

This is an abbreviated version!
For detailed information about sphingoid base N-palmitoyltransferase, go to the full flat file.

Reaction

Synonyms

CerS4, CerS5, LASS5, longevity assurance homolog 5, mammalian ceramide synthase 5

ECTree

     2 Transferases

         2.3 Acyltransferases

             2.3.1 Transferring groups other than aminoacyl groups

                2.3.1.291 sphingoid base N-palmitoyltransferase

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Results	in table
16	AA Sequence
8	Application
5	Cloned(Commentary)
6	Expression
10	General Information
2	Inhibitors
2	Localization
2	Natural Substrates/ Products (Substrates)
23	Organism
2	Pathway
5	Posttranslational Modification
2	Protein Variants
1	Reaction
23	Reference
23	Source Tissue
10	Substrates and Products (Substrate)
14	Synonyms
1	Systematic Name

Systematic Name

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Systematic Name on EC 2.3.1.291 - sphingoid base N-palmitoyltransferase

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SYSTEMATIC NAME

IUBMB Comments

palmitoyl-CoA:sphingoid base N-palmitoyltransferase

Mammals have six ceramide synthases that exhibit relatively strict specificity regarding the chain-length of their acyl-CoA substrates. Ceramide synthase 5 (CERS5) is specific for palmitoyl-CoA as the acyl donor. It can use multiple sphingoid bases including sphinganine, sphingosine, and phytosphingosine.