2.3.1.291: sphingoid base N-palmitoyltransferase

This is an abbreviated version!
For detailed information about sphingoid base N-palmitoyltransferase, go to the full flat file.

Reaction

Synonyms

CerS4, CerS5, LASS5, longevity assurance homolog 5, mammalian ceramide synthase 5

ECTree

2 Transferases

2.3 Acyltransferases

2.3.1 Transferring groups other than aminoacyl groups

2.3.1.291 sphingoid base N-palmitoyltransferase

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Results	in table
16	AA Sequence
8	Application
5	Cloned(Commentary)
6	Expression
10	General Information
2	Inhibitors
2	Localization
2	Natural Substrates/ Products (Substrates)
23	Organism
2	Pathway
5	Posttranslational Modification
2	Protein Variants
1	Reaction
23	Reference
23	Source Tissue
10	Substrates and Products (Substrate)
14	Synonyms
1	Systematic Name

Expression

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Expression on EC 2.3.1.291 - sphingoid base N-palmitoyltransferase

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ionizing radiation induces de novo synthesis of ceramide by specifically activating CerS isoforms 2, 5, and 6

Homo sapiens

Q8N5B7

753223

presence of fenritinide leads to transcriptional downregulation of Cers5

2 entries

pulmonary LASS5 is developmentally regulated, but its expression is spatially and gender nonspecific

2 entries

the expression of CerS1 and CerS5 mRNA, encoding the ceramide synthases with substrate preference for C16:0 and C18:0 acyl chains, respectively, is downregulated in skeletal muscle of aged mice

Mus musculus

Q9D6K9

752426