2.3.1.291: sphingoid base N-palmitoyltransferase
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For detailed information about sphingoid base N-palmitoyltransferase, go to the full flat file.
Reaction
Synonyms
CerS4, CerS5, LASS5, longevity assurance homolog 5, mammalian ceramide synthase 5
ECTree
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Posttranslational Modification
Posttranslational Modification on EC 2.3.1.291 - sphingoid base N-palmitoyltransferase
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glycoprotein
phosphoprotein
phosphorylation modestly increases the catalytic activities of Cers5
phosphoprotein
isoform Cers5 is phosphorylated at the cytoplasmic C-terminal region. Treatment with lambda protein phosphatase reduces the activity by 27%
phosphoprotein
dephosphorylation of endogenous ceramide synthases in the mouse brain leads to modestly reduced activity toward the Cers5/6 substrate C16:0-CoA