1.14.14.87: 2-hydroxyisoflavanone synthase

This is an abbreviated version!
For detailed information about 2-hydroxyisoflavanone synthase, go to the full flat file.

Reaction

Synonyms

2-HIS, 2-hydroxyisoflavanone synthase, 2-hydroxyisoflavanone synthase 1, 2HI synthase, CYP93C, Cyp93C1, CYP93C18, CYP93C2, Cyp93C20, CYT93C, EC 1.14.13.136, EC 1.14.13.86, GmIFS, GmIFS1, IFS, IFS1, IFS2, IFS2-12, isoflavone synthase, isoflavone synthase 2

ECTree

     1 Oxidoreductases

         1.14 Acting on paired donors, with incorporation or reduction of molecular oxygen

             1.14.14 With reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen into the other donor

                1.14.14.87 2-hydroxyisoflavanone synthase

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Results	in table
1	Activating Compound
19	AA Sequence
1	Application
9	Cloned(Commentary)
6	Cofactor
3	Expression
10	General Information
5	Inhibitors
4	KM Value [mM]
8	Localization
1	Metals/Ions
1	Molecular Weight [Da]
6	Natural Substrates/ Products (Substrates)
22	Organism
5	Pathway
2	pH Optimum
2	pH Range
9	Protein Variants
2	Reaction
21	Reference
7	Source Tissue
20	Substrates and Products (Substrate)
2	Subunits
37	Synonyms
1	Systematic Name

Inhibitors

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Inhibitors on EC 1.14.14.87 - 2-hydroxyisoflavanone synthase

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INHIBITOR

ORGANISM

UNIPROT

COMMENTARY

LITERATURE

IMAGE

Ancymidol

Pueraria montana var. lobata

-

complete inhibition at 1 mM

714992

CO2

Pueraria montana var. lobata

-

52% inhibition in the presence of CO2 gas

714992

Metyrapone

Pueraria montana var. lobata

-

complete inhibition at 0.1 mM

714992

SKF 525-A

Pueraria montana var. lobata

-

73% inhibition at 2 mM

714992

uniconazole

Pueraria montana var. lobata

-

complete inhibition at 0.1 mM

714992