EC Number |
Recommended Name |
Source Tissue |
Reference |
---|
1.1.1.22 | UDP-glucose 6-dehydrogenase |
breast |
- |
762065 |
1.1.1.27 | L-lactate dehydrogenase |
breast |
- |
740255 |
1.1.1.37 | malate dehydrogenase |
breast |
- |
760668 |
1.1.1.62 | 17beta-estradiol 17-dehydrogenase |
breast |
- |
656371, 686263, 713021, 740542 |
1.1.1.8 | glycerol-3-phosphate dehydrogenase (NAD+) |
breast |
- |
762072 |
1.14.11.2 | procollagen-proline 4-dioxygenase |
breast |
- |
744594 |
1.14.13.8 | flavin-containing monooxygenase |
breast |
- |
673313 |
1.14.14.79 | docosahexaenoic acid omega-hydroxylase |
breast |
- |
728344 |
1.14.15.18 | calcidiol 1-monooxygenase |
breast |
- |
671357, 672857, 675686, 695621 |
1.2.1.105 | 2-oxoglutarate dehydrogenase system |
breast |
- |
672280 |
1.2.1.36 | retinal dehydrogenase |
breast |
- |
655948 |
1.6.3.1 | NAD(P)H oxidase (H2O2-forming) |
breast |
- |
711688 |
2.3.1.135 | phosphatidylcholine-retinol O-acyltransferase |
breast |
- |
674069 |
2.3.1.24 | sphingosine N-acyltransferase |
breast |
- |
736471 |
2.4.1.17 | glucuronosyltransferase |
breast |
- |
488786, 488790, 735649, 759116 |
2.7.1.137 | phosphatidylinositol 3-kinase |
breast |
- |
640952 |
2.7.1.147 | ADP-specific glucose/glucosamine kinase |
breast |
- |
723169 |
2.7.1.154 | phosphatidylinositol-4-phosphate 3-kinase |
breast |
- |
640931, 640952 |
2.7.1.32 | choline kinase |
breast |
- |
673201 |
2.7.1.91 | sphingosine kinase |
breast |
- |
671356, 702084 |
2.7.10.1 | receptor protein-tyrosine kinase |
breast |
- |
661457 |
2.7.11.1 | non-specific serine/threonine protein kinase |
breast |
- |
708371 |
2.7.11.10 | IkappaB kinase |
breast |
- |
676886 |
2.7.11.13 | protein kinase C |
breast |
- |
695064 |
2.7.11.18 | myosin-light-chain kinase |
breast |
- |
640647 |
2.7.11.19 | phosphorylase kinase |
breast |
- |
676038 |
2.7.11.21 | polo kinase |
breast |
- |
703598 |
2.7.11.24 | mitogen-activated protein kinase |
breast |
- |
665638 |
2.7.11.25 | mitogen-activated protein kinase kinase kinase |
breast |
- |
665600 |
2.7.8.2 | diacylglycerol cholinephosphotransferase |
breast |
- |
705452 |
2.8.2.2 | alcohol sulfotransferase |
breast |
- |
675680 |
2.8.2.29 | [heparan sulfate]-glucosamine 3-sulfotransferase 2 |
breast |
- |
662996 |
2.8.2.4 | estrone sulfotransferase |
breast |
- |
671361, 674994, 691194, 691624 |
3.1.3.11 | fructose-bisphosphatase |
breast |
- |
690771 |
3.1.3.46 | fructose-2,6-bisphosphate 2-phosphatase |
breast |
- |
664248 |
3.1.3.67 | phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase |
breast |
- |
694494 |
3.1.6.12 | N-acetylgalactosamine-4-sulfatase |
breast |
- |
707573 |
3.1.6.2 | steryl-sulfatase |
breast |
- |
714906 |
3.2.1.51 | alpha-L-fucosidase |
breast |
- |
739213 |
3.3.2.11 | cholesterol-5,6-oxide hydrolase |
breast |
- |
752861 |
3.4.13.9 | Xaa-Pro dipeptidase |
breast |
- |
707010 |
3.4.14.5 | dipeptidyl-peptidase IV |
breast |
- |
695514 |
3.4.19.12 | ubiquitinyl hydrolase 1 |
breast |
- |
698156 |
3.4.19.6 | pyroglutamyl-peptidase II |
breast |
- |
753360 |
3.4.19.9 | folate gamma-glutamyl hydrolase |
breast |
- |
683368 |
3.4.21.109 | matriptase |
breast |
- |
683492 |
3.4.21.117 | stratum corneum chymotryptic enzyme |
breast |
- |
647332, 707996 |
3.4.21.119 | kallikrein 13 |
breast |
- |
647372, 647373 |
3.4.21.42 | complement subcomponent C1s |
breast |
- |
753047 |
3.4.21.B10 | neurosin |
breast |
- |
731397 |
3.4.21.B12 | prostase |
breast |
- |
647334 |
3.4.21.B39 | stratum corneum tryptic enzyme |
breast |
- |
680680 |
3.4.21.B41 | kallikrein 10 |
breast |
- |
678524 |
3.4.22.15 | cathepsin L |
breast |
- |
678521 |
3.4.23.B24 | signal peptide peptidase |
breast |
- |
754940 |
3.4.24.35 | gelatinase B |
breast |
- |
696965, 710650 |
3.4.24.56 | insulysin |
breast |
- |
683571 |
3.4.24.B3 | matrix metalloproteinase-11 |
breast |
- |
708156 |
3.4.24.B7 | matrix metalloproteinase-26 |
breast |
- |
710794 |
3.5.1.88 | peptide deformylase |
breast |
- |
733571 |
3.5.4.4 | adenosine deaminase |
breast |
- |
668272, 718704 |
3.6.1.29 | bis(5'-adenosyl)-triphosphatase |
breast |
- |
289061, 668869 |
5.1.99.4 | alpha-methylacyl-CoA racemase |
breast |
- |
704836 |
5.6.1.7 | chaperonin ATPase |
breast |
- |
749858 |
6.4.1.1 | pyruvate carboxylase |
breast |
- |
746189 |
7.6.2.3 | ABC-type glutathione-S-conjugate transporter |
breast |
- |
748624 |
2.7.1.40 | pyruvate kinase |
breast |
activity in tumor tissue is higher than in normal tissue |
660823 |
2.1.1.63 | methylated-DNA-[protein]-cysteine S-methyltransferase |
breast |
AGT expression is increased in breast cancer compared to normal breast |
673219 |
3.4.21.B28 | fibroblast activation protein alpha subunit |
breast |
cancer stroma cells |
650762 |
2.8.2.2 | alcohol sulfotransferase |
breast |
cancer tissue |
645741 |
3.5.4.3 | guanine deaminase |
breast |
cancerous and non-cancerous |
209600 |
3.4.21.109 | matriptase |
breast |
co-expression of matriptase and its substrate serine protease prostasin |
717902 |
3.4.21.B6 | prostasin |
breast |
co-expression of matriptase and its substrate serine protease prostasin |
717902 |
2.4.2.4 | thymidine phosphorylase |
breast |
ductal carcinoma in situ and invasive elements |
638469 |
1.14.15.18 | calcidiol 1-monooxygenase |
breast |
enzyme expression analysis in different samples of women with and without breast cancer, no correlation with breast cancer development |
675679 |
4.1.1.17 | ornithine decarboxylase |
breast |
epithelial cells |
695299 |
2.7.10.2 | non-specific protein-tyrosine kinase |
breast |
epithelium, Syk occurs in MDA-MB-468 cells, but not in BT-549 cells |
661457 |
1.3.1.21 | 7-dehydrocholesterol reductase |
breast |
exocrine, high desmosterol synthesis |
656819 |
3.4.22.B29 | calpain 9 |
breast |
expression analysis |
731549 |
3.4.21.B41 | kallikrein 10 |
breast |
expression in normal cells, but no expression in breast cancer cells |
670979 |
7.2.2.9 | P-type Cu2+ transporter |
breast |
expression is greater in lactating tissue than in nonlactating tissue, detected in luminal epithelial cells of the alveoli and ducts but not in myoepithelial cells |
246918 |
3.4.21.B39 | stratum corneum tryptic enzyme |
breast |
expression levels of KLK5 and KLK7 in benign breast tissues and metastases, and the relationship between KLK5 and KLK7 expression and and clinicopathological factors. mRNA levels of KLK5 and KLK7 in normal breast tissues, benign breast tissues, primary tumors, and lymph node metastases, overview. mRNA levels of KLK5 and KLK7 are both downregulated in breast cancers relative to normal and benign tissues, and downregulated in metastases compared to primary cancers |
707996 |
3.1.3.11 | fructose-bisphosphatase |
breast |
FBP1 is commonly upregulated in tumor tissues compared with non-tumor tissues regardless of histological type. Enzyme expression profiles of breast cancer cells reveals that cells exhibiting high expression of FBP1 have a lower activity of Wnt/beta-catenin pathway |
750008 |
3.4.21.77 | semenogelase |
breast |
female |
647332 |
3.4.24.56 | insulysin |
breast |
female breast |
696530 |
3.1.6.2 | steryl-sulfatase |
breast |
fibroblasts from normal and malignant breast tissue, study of the regulation of STS mRNA expression |
656640 |
2.7.10.2 | non-specific protein-tyrosine kinase |
breast |
Frk, Brk, Src, Fyn, Yes |
660885 |
3.4.21.B43 | kallikrein 12 |
breast |
gene expression of the enzyme is down-regulated in breast cancer |
647367 |
2.3.1.5 | arylamine N-acetyltransferase |
breast |
healthy and neoplastic tissue |
676155 |
3.4.21.B39 | stratum corneum tryptic enzyme |
breast |
high expression |
670978 |
3.4.21.B10 | neurosin |
breast |
high expression level |
647332 |
3.4.21.B39 | stratum corneum tryptic enzyme |
breast |
high expression level |
647332 |
3.4.22.38 | cathepsin K |
breast |
high expression level |
697375 |
2.7.10.1 | receptor protein-tyrosine kinase |
breast |
high expression level of ErbB1 receptor |
660873 |
6.3.4.3 | formate-tetrahydrofolate ligase |
breast |
higher expression level |
660866 |
3.2.1.35 | hyaluronoglucosaminidase |
breast |
HPH-20 |
664596 |
2.4.1.17 | glucuronosyltransferase |
breast |
identification of isozyme UGT1A10 in non-malignant and malignant human breast tissues, UGT1A10 and UGT2B7 mRNAs are differentially expressed among healthy and malignant specimens, in African American women, UGT1A10 expression is significantly decreased in breast carcinomas in comparison to healthy, while among Caucasian women, overview |
695149 |
5.3.99.3 | prostaglandin-E synthase |
breast |
in normal breast the enzyme is seen in myoepithelial cells and in stromal fibroblasts and vascular smooth muscle, in breast disease, the enzyme is observed in epithelial cells adjacent to cancer, in scattered foci of fibrocystic disease, in ductal carcinoma in situ and in invasive cancers, in addition to myoepithelial cells |
662700 |
3.4.21.B41 | kallikrein 10 |
breast |
KLK10 is not methylated in normal breast tissues and fibroadenomas while it is in 5 of 10 breast tumors and in 1 of 10 matching normal tissues |
690443 |
3.4.21.35 | tissue kallikrein |
breast |
KLK4 |
678522 |