EC Number |
Recommended Name |
Source Tissue |
Reference |
---|
1.1.1.146 | 11beta-hydroxysteroid dehydrogenase |
adipocyte |
- |
668379, 669504, 697625, 700121, 700179, 700180, 712594, 740806 |
1.1.1.146 | 11beta-hydroxysteroid dehydrogenase |
adipocyte |
epididymal fat, presence of a functional glucose-6-phosphate-transporter hexose-6-phosphate dehydrogenase 11beta-hydroxysteroid dehydrogenase type 1 system |
692078 |
1.1.1.146 | 11beta-hydroxysteroid dehydrogenase |
adipocyte |
methionine restriction induces isoform 11beta-HSD1 activity in all types of adipose tissue examined, correlating with increased tissue corticosterone. Inverse relationship between 11beta-HSD1 activity and adipocyte size is observed. Methionine restriction additionally increases adipose triglyceride lipase and acetyl-coenzyme A carboxylase protein levels |
688225 |
1.1.1.205 | IMP dehydrogenase |
adipocyte |
- |
702061 |
1.1.1.42 | isocitrate dehydrogenase (NADP+) |
adipocyte |
- |
656247, 761047 |
1.1.1.44 | phosphogluconate dehydrogenase (NADP+-dependent, decarboxylating) |
adipocyte |
- |
667411, 685541 |
1.1.1.51 | 3(or 17)beta-hydroxysteroid dehydrogenase |
adipocyte |
real-time RT-PCR expression 17beta-HSD type 2 analysis |
741000 |
1.1.1.62 | 17beta-estradiol 17-dehydrogenase |
adipocyte |
- |
699843 |
1.1.1.8 | glycerol-3-phosphate dehydrogenase (NAD+) |
adipocyte |
- |
699948 |
1.1.1.95 | phosphoglycerate dehydrogenase |
adipocyte |
- |
287528 |
1.1.1.B40 | 11beta-hydroxysteroid dehydrogenase (NAD+) |
adipocyte |
- |
668379 |
1.11.1.9 | glutathione peroxidase |
adipocyte |
pGPx is expressed during bovine adipocyte differentiation, transcriptional control of pGPx in cattle might be carried out by C/EBPdelta |
672988 |
1.13.11.20 | cysteine dioxygenase |
adipocyte |
- |
695529 |
1.13.11.31 | arachidonate 12-lipoxygenase |
adipocyte |
- |
743718 |
1.13.11.33 | arachidonate 15-lipoxygenase |
adipocyte |
- |
742239, 743718 |
1.13.11.63 | beta-carotene 15,15'-dioxygenase |
adipocyte |
- |
728342, 728552 |
1.14.11.4 | procollagen-lysine 5-dioxygenase |
adipocyte |
- |
745769 |
1.14.11.68 | [histone H3]-trimethyl-L-lysine27 demethylase |
adipocyte |
- |
753372 |
1.14.15.18 | calcidiol 1-monooxygenase |
adipocyte |
- |
699840 |
1.14.19.1 | stearoyl-CoA 9-desaturase |
adipocyte |
- |
687766, 746212 |
1.14.99.66 | [histone H3]-N6,N6-dimethyl-L-lysine4 FAD-dependent demethylase |
adipocyte |
- |
754828 |
1.2.1.104 | pyruvate dehydrogenase system |
adipocyte |
- |
760172 |
1.2.1.104 | pyruvate dehydrogenase system |
adipocyte |
brown adipocyte |
762889 |
1.2.4.1 | pyruvate dehydrogenase (acetyl-transferring) |
adipocyte |
brown adipocyte |
762889 |
1.21.99.3 | thyroxine 5-deiodinase |
adipocyte |
cell culture |
644799 |
1.21.99.3 | thyroxine 5-deiodinase |
adipocyte |
isozyme type III |
644799 |
1.21.99.4 | thyroxine 5'-deiodinase |
adipocyte |
- |
644806 |
1.21.99.4 | thyroxine 5'-deiodinase |
adipocyte |
isozyme type II |
644806 |
1.3.1.48 | 13,14-dehydro-15-oxoprostaglandin 13-reductase |
adipocyte |
- |
687562 |
1.3.3.6 | acyl-CoA oxidase |
adipocyte |
- |
671758 |
1.3.8.7 | medium-chain acyl-CoA dehydrogenase |
adipocyte |
- |
656794 |
1.3.99.23 | all-trans-retinol 13,14-reductase |
adipocyte |
- |
700994, 763507 |
1.4.3.21 | primary-amine oxidase |
adipocyte |
- |
689376, 701561, 701612, 726290 |
1.4.3.21 | primary-amine oxidase |
adipocyte |
major SSAO form expressed in mouse adipocytes is encoded by the AOC3 gene |
688487 |
1.4.3.21 | primary-amine oxidase |
adipocyte |
most of the SSAO found in adipose tissue originates from mature adipocytes |
688255 |
1.4.3.21 | primary-amine oxidase |
adipocyte |
SSAO inhibition is not sufficient to impair fat deposition. However, combined monoamine oxidase (EC 1.4.3.4) inhibition and SSAO inhibition limits adiposity in non-obese as well as in obese rats |
689377 |
1.4.3.21 | primary-amine oxidase |
adipocyte |
the major SSAO form expressed in mouse adipocytes is encoded by the AOC3 gene |
688487 |
1.4.3.4 | monoamine oxidase |
adipocyte |
- |
689376 |
1.4.3.4 | monoamine oxidase |
adipocyte |
in human subcutaneous adipose tissue, the adipocyte-enriched fraction exhibits seven-fold higher amine oxidase activity and contains 3- to 7-fold higher levels of mRNAs encoded by MAO-A and MAO-B genes than the stroma-vascular fraction. MAO-A gene accounts for the majority of the respective MAO and SSAO activities in human adipose tissue. Most of the SSAO and MAO found in adipose tissue originated from mature adipocytes |
685418 |
1.4.3.4 | monoamine oxidase |
adipocyte |
most of the monoamine oxidase found in adipose tissue originates from mature adipocytes |
688255 |
1.4.3.4 | monoamine oxidase |
adipocyte |
SSAO inhibition is not sufficient to impair fat deposition. Combined MAO and SSAO inhibition limits adiposity in non-obese as well as in obese rats |
689377 |
1.6.3.1 | NAD(P)H oxidase (H2O2-forming) |
adipocyte |
isoform Nox4 is expressed at high levels in white and brown preadipocytes. Differentiation into adipocytes results in a decrease in their NOX4 mRNA content. In intact adipose tissue, the majority of NOX4 expressing cells are localized within the preadipocyte containing stromal/vascular fracftion. Alterations in NOX4 expression reflects changes in the ratio of adipocyte/interstitial fractions |
685345 |
2.1.1.1 | nicotinamide N-methyltransferase |
adipocyte |
- |
701990 |
2.1.1.1 | nicotinamide N-methyltransferase |
adipocyte |
NNMT expression profile, overview |
701990 |
2.1.1.204 | tRNA (cytosine38-C5)-methyltransferase |
adipocyte |
- |
-, 736018 |
2.1.1.319 | type I protein arginine methyltransferase |
adipocyte |
Prmt1 is highly expressed in major metabolic organs and cell types, including thermogenic fat tissue and adipocytes |
756600 |
2.1.1.348 | mRNA m6A methyltransferase |
adipocyte |
- |
757661 |
2.3.1.108 | alpha-tubulin N-acetyltransferase |
adipocyte |
acetylation of alpha-tubulin is up-regulated during adipogenesis, and adipocyte development is dependent on alpha-tubulin acetylation |
735631 |
2.3.1.15 | glycerol-3-phosphate 1-O-acyltransferase |
adipocyte |
- |
701623, 702011, 756106 |
2.3.1.15 | glycerol-3-phosphate 1-O-acyltransferase |
adipocyte |
GPAT3 mRNA is dramatically upregulated during adipocyte differentiation |
676839 |
2.3.1.15 | glycerol-3-phosphate 1-O-acyltransferase |
adipocyte |
mitochondrial acyltransferase |
486376 |
2.3.1.15 | glycerol-3-phosphate 1-O-acyltransferase |
adipocyte |
the expression of GPAT2 is downregulated when 3T3-L1 cells differentiate into adipocytes, while GPAT1, 3, and 4 are upregulated (10fold, over 60, and 5fold, respectively) |
757868 |
2.3.1.15 | glycerol-3-phosphate 1-O-acyltransferase |
adipocyte |
the expression of GPAT2 is downregulated when 3T3-L1 cells differentiate into adipocytes, while GPAT1, 3, and 4 are upregulated 10fold, over 60fold, and 5fold, respectively |
757868 |
2.3.1.20 | diacylglycerol O-acyltransferase |
adipocyte |
- |
-, 486338, 486485, 486487, 486489, 486495, 486505, 486506, 486512, 486513 |
2.3.1.20 | diacylglycerol O-acyltransferase |
adipocyte |
isolated from parametrial adipose |
486484 |
2.3.1.21 | carnitine O-palmitoyltransferase |
adipocyte |
- |
486560, 486577 |
2.3.1.22 | 2-acylglycerol O-acyltransferase |
adipocyte |
- |
757377 |
2.3.1.23 | 1-acylglycerophosphocholine O-acyltransferase |
adipocyte |
by retrieving LPCAT3 expression pattern from Genevestigator |
688774 |
2.3.1.42 | glycerone-phosphate O-acyltransferase |
adipocyte |
- |
486338, 486955, 486974 |
2.3.1.51 | 1-acylglycerol-3-phosphate O-acyltransferase |
adipocyte |
- |
671597, 756108, 756599 |
2.3.1.51 | 1-acylglycerol-3-phosphate O-acyltransferase |
adipocyte |
isozyme AGPAT2 |
674530 |
2.3.1.57 | diamine N-acetyltransferase |
adipocyte |
- |
757571 |
2.3.3.8 | ATP citrate synthase |
adipocyte |
- |
736797 |
2.4.1.11 | glycogen(starch) synthase |
adipocyte |
3T3-L1 |
488441, 488447 |
2.4.2.12 | nicotinamide phosphoribosyltransferase |
adipocyte |
- |
735872 |
2.4.3.1 | beta-galactoside alpha-(2,6)-sialyltransferase |
adipocyte |
- |
759485 |
2.5.1.60 | protein geranylgeranyltransferase type II |
adipocyte |
- |
638598 |
2.6.1.1 | aspartate transaminase |
adipocyte |
- |
674846 |
2.6.1.1 | aspartate transaminase |
adipocyte |
differentiated from 3T3-L1 fibroblasts |
639866 |
2.7.1.1 | hexokinase |
adipocyte |
very low expression |
703959 |
2.7.1.113 | deoxyguanosine kinase |
adipocyte |
- |
661040 |
2.7.1.137 | phosphatidylinositol 3-kinase |
adipocyte |
- |
640905, 640908, 640911, 640924, 709772 |
2.7.1.137 | phosphatidylinositol 3-kinase |
adipocyte |
3T3-L1 |
640849, 640863 |
2.7.1.137 | phosphatidylinositol 3-kinase |
adipocyte |
during differentiation of 3T3-L1 cells into adipocytes, isoform p110b is up-regulated approximately 10-fold, expression of p110a is unaltered |
640863 |
2.7.1.137 | phosphatidylinositol 3-kinase |
adipocyte |
insulin-sensitive mouse 3T3-L1 adipocytes |
640921 |
2.7.1.137 | phosphatidylinositol 3-kinase |
adipocyte |
primary, obtained from subcutaneous tissue biopsies performed on two lean non-diabetic male subjects |
709772 |
2.7.1.150 | 1-phosphatidylinositol-3-phosphate 5-kinase |
adipocyte |
- |
660790 |
2.7.1.30 | glycerol kinase |
adipocyte |
There is no difference in glycerol mRNA level between control 3T3-L1 adipocytes and 3T3-L1 Aqp7-RNAi transfected adipocytes, whereas a 4fold enzymatic activation of glycerol kinase is observable in Aqp7 knockout adipocytes (activity assay: 50 mM TrisHCl, pH 7.2, 5 mM ATP, 10 mM MgCl2, 100 mM KCl, 2.5 mM DTT, 4 mM glycerol, 500 microM 3H-glycerol, for 90 min at 37°C). |
682503 |
2.7.1.40 | pyruvate kinase |
adipocyte |
expression of M2-type pyruvate kinase isoenzyme |
721787 |
2.7.1.67 | 1-phosphatidylinositol 4-kinase |
adipocyte |
- |
641796, 676001 |
2.7.1.74 | deoxycytidine kinase |
adipocyte |
- |
661040 |
2.7.10.1 | receptor protein-tyrosine kinase |
adipocyte |
- |
671353 |
2.7.11.1 | non-specific serine/threonine protein kinase |
adipocyte |
- |
-, 723027, 738003, 761503 |
2.7.11.1 | non-specific serine/threonine protein kinase |
adipocyte |
white, brown and beige adipocyte |
742242 |
2.7.11.11 | cAMP-dependent protein kinase |
adipocyte |
- |
671678, 693043, 694155 |
2.7.11.12 | cGMP-dependent protein kinase |
adipocyte |
- |
737600 |
2.7.11.13 | protein kinase C |
adipocyte |
- |
676029 |
2.7.11.15 | beta-adrenergic-receptor kinase |
adipocyte |
- |
661684, 724817 |
2.7.11.27 | [acetyl-CoA carboxylase] kinase |
adipocyte |
- |
761916 |
2.7.11.31 | [hydroxymethylglutaryl-CoA reductase (NADPH)] kinase |
adipocyte |
- |
692365, 760351, 760910 |
2.7.11.31 | [hydroxymethylglutaryl-CoA reductase (NADPH)] kinase |
adipocyte |
primary |
665636 |
2.7.11.4 | [3-methyl-2-oxobutanoate dehydrogenase (acetyl-transferring)] kinase |
adipocyte |
- |
640583 |
2.7.4.21 | inositol-hexakisphosphate 5-kinase |
adipocyte |
- |
738392 |
2.7.7.14 | ethanolamine-phosphate cytidylyltransferase |
adipocyte |
- |
671816 |
2.7.7.14 | ethanolamine-phosphate cytidylyltransferase |
adipocyte |
high Pcyt2 mRNA content. Negligible amount of Pcyt2beta mRNA, high amount of Pcyt2alpha mRNA |
671816 |
2.7.8.1 | ethanolaminephosphotransferase |
adipocyte |
- |
644323 |
2.7.8.2 | diacylglycerol cholinephosphotransferase |
adipocyte |
- |
644323 |
2.8.1.1 | thiosulfate sulfurtransferase |
adipocyte |
- |
739155 |
2.8.2.4 | estrone sulfotransferase |
adipocyte |
- |
725979 |
2.8.2.4 | estrone sulfotransferase |
adipocyte |
EST is predominantly expressed in stromal vascular cells (pre-adipocytes). Consistent with the pre-adipocyte pattern of expression, the expression of EST is dramatically reduced in differentiated 3T3-L1 cells or mature primary adipocytes |
-, 760317 |