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Information on EC 1.3.1.48 - 13,14-dehydro-15-oxoprostaglandin 13-reductase

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EC Tree
IUBMB Comments
Reduces 13,14-dehydro-15-oxoprostaglandins to 13,14-dihydro derivatives. The enzyme from placenta is specific for NAD+.
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Word Map
The expected taxonomic range for this enzyme is: Eukaryota, Bacteria
Synonyms
prostaglandin reductase 1, ltbdh/pgr, prostaglandin delta13-reductase, leukotriene b4 dehydrogenase, 15-oxoprostaglandin 13-reductase, pgr-2, pg reductase, 15-keto-pg reductase, 15-oxoprostaglandin-delta13-reductase, delta13-15-ketoprostaglandin reductase, more
REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
11alpha-hydroxy-9,15-dioxoprostanoate + NAD(P)+ = (13E)-11alpha-hydroxy-9,15-dioxoprost-13-enoate + NAD(P)H + H+
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