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EC 2.3.1.177 Details
EC number
2.3.1.177
Accepted name
3,5-dihydroxybiphenyl synthase
Reaction
3 malonyl-CoA + benzoyl-CoA = 4 CoA + 3,5-dihydroxybiphenyl + 4 CO2
Other name(s)
BIS1, biphenyl synthase (ambiguous)
Systematic name
malonyl-CoA:benzoyl-CoA malonyltransferase
CAS registry number
1217551-24-0
Comment
A polyketide synthase that is involved in the production of the phytoalexin aucuparin. 2-Hydroxybenzoyl-CoA can also act as substrate but it leads to the derailment product 4-hydroxycoumarin (cf. EC 2.3.1.208, 4-hydroxycoumarin synthase) [2]. This enzyme uses the same starter substrate as EC 2.3.1.151, benzophenone synthase.
History
created 2006, modified 2012
EC Tree
2.3.1.55 created 1976, deleted 1999
2.3.1.120 created 1990, deleted 1992
2.3.1.124 created 1990, deleted 1992