2.4.2.60: cysteine-dependent adenosine diphosphate thiazole synthase
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For detailed information about cysteine-dependent adenosine diphosphate thiazole synthase, go to the full flat file.
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Synonyms
ADP-thiazole synthase, CyPBP37, NCU06110, Thi-4, THI1, Thi4
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Systematic Name
Systematic Name on EC 2.4.2.60 - cysteine-dependent adenosine diphosphate thiazole synthase
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NAD+:glycine ADP-D-ribosyltransferase (dehydroalanine-producing)
This iron dependent enzyme, found in fungi, plants, and some archaea, is involved in the thiamine phosphate biosynthesis pathway. It is a single turn-over enzyme since the cysteine residue is not regenerated in vivo [3]. The homologous enzyme in archaea (EC 2.4.2.59, sulfide-dependent adenosine diphosphate thiazole synthase) uses sulfide as sulfur donor.