Any feedback?
Please rate this page
(all_enzymes.php)
(0/150)

BRENDA support

2.4.2.60: cysteine-dependent adenosine diphosphate thiazole synthase

This is an abbreviated version!
For detailed information about cysteine-dependent adenosine diphosphate thiazole synthase, go to the full flat file.

Reaction

NAD+
+
glycine
+
[ADP-thiazole synthase]-L-cysteine
=
nicotinamide
+
ADP-5-ethyl-4-methylthiazole-2-carboxylate
+
[ADP-thiazole synthase]-dehydroalanine
+ 3 H2O

Synonyms

ADP-thiazole synthase, CyPBP37, NCU06110, Thi-4, THI1, Thi4

ECTree

     2 Transferases
         2.4 Glycosyltransferases
             2.4.2 Pentosyltransferases
                2.4.2.60 cysteine-dependent adenosine diphosphate thiazole synthase

Expression

Expression on EC 2.4.2.60 - cysteine-dependent adenosine diphosphate thiazole synthase

Please wait a moment until all data is loaded. This message will disappear when all data is loaded.
EXPRESSION
ORGANISM
UNIPROT
LITERATURE
expression is completely repressed throughout batch culture by thiamine at a concentration around 1 microM, but high level constitutive expression occurs in thiamine-free medium
expression is induced by osmotic stress, salinity stress and oxidative stress
-
expression is induced by stress
expression is induced by to oxidative and osmotic stress
-
expression is induced when the intracellular concentration of thiamine falls to 20 pmol per 10 million cells
presence of thiamine does not suppress expression
the expression of CyPBP37 is repressed by thiamine but not by thiazole in the growth medium