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2.3.2.33: RCR-type E3 ubiquitin transferase

This is an abbreviated version!
For detailed information about RCR-type E3 ubiquitin transferase, go to the full flat file.

Word Map on EC 2.3.2.33

Reaction

[E2 ubiquitin-conjugating enzyme]-S-ubiquitinyl-L-cysteine
+
[acceptor protein]-L-threonine
=
[E2 ubiquitin-conjugating enzyme]-L-cysteine
+
[acceptor protein]-3-O-ubiquitinyl-L-threonine

Synonyms

E3 ubiquitin-protein ligase, MYCBP2, PHR1, RPM-1

ECTree

     2 Transferases
         2.3 Acyltransferases
             2.3.2 Aminoacyltransferases
                2.3.2.33 RCR-type E3 ubiquitin transferase

Disease

Disease on EC 2.3.2.33 - RCR-type E3 ubiquitin transferase

Please use the Disease Search for a specific query.
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DISEASE
TITLE OF PUBLICATION
LINK TO PUBMED
Colonic Neoplasms
Epigenetically regulated miR-1247 functions as a novel tumour suppressor via MYCBP2 in methylator colon cancers.
Hyperalgesia
MYCBP2 Is a Guanosine Exchange Factor for Ran Protein and Determines Its Localization in Neurons of Dorsal Root Ganglia.
The ubiquitin ligase MYCBP2 regulates transient receptor potential vanilloid receptor 1 (TRPV1) internalization through inhibition of p38 MAPK signaling.
Infections
A Chimeric Pneumovirus Fusion Protein Carrying Neutralizing Epitopes of Both MPV and RSV.
Melanoma
miR-92a-3p and MYCBP2 are involved in MS-275-induced and c-myc-mediated TRAIL-sensitivity in melanoma cells.
Neoplasms
Epigenetically regulated miR-1247 functions as a novel tumour suppressor via MYCBP2 in methylator colon cancers.
Precursor Cell Lymphoblastic Leukemia-Lymphoma
Clinical significance of high c-MYC and low MYCBP2 expression and their association with Ikaros dysfunction in adult acute lymphoblastic leukemia.
Prostatic Neoplasms
MiR-1247-5p is overexpressed in castration resistant prostate cancer and targets MYCBP2.
Virus Diseases
A Chimeric Pneumovirus Fusion Protein Carrying Neutralizing Epitopes of Both MPV and RSV.