EC Number |
Recommended Name |
Source Tissue |
Reference |
---|
1.1.1.1 | alcohol dehydrogenase |
adrenal gland |
- |
285604 |
1.1.1.145 | 3beta-hydroxy-DELTA5-steroid dehydrogenase |
adrenal gland |
- |
389369, 389374, 389376, 389377, 389378, 389389, 389391, 389395, 389400, 655345, 668423, 670037, 725447, 740418, 740998 |
1.1.1.145 | 3beta-hydroxy-DELTA5-steroid dehydrogenase |
adrenal gland |
3beta-HSD II |
389387, 389395 |
1.1.1.145 | 3beta-hydroxy-DELTA5-steroid dehydrogenase |
adrenal gland |
3beta-HSD21 is selectively expressed in adrenal glands and ovaries |
763397 |
1.1.1.145 | 3beta-hydroxy-DELTA5-steroid dehydrogenase |
adrenal gland |
3betaHSD I |
389383 |
1.1.1.145 | 3beta-hydroxy-DELTA5-steroid dehydrogenase |
adrenal gland |
HSD3B2 and CYB5A are immonolocalized in normal human adrenal glands. Their co-expression is demonstrated in the cortical cells located at the border between the zona fasciculata and zona reticularis in normal human adrenal |
725816 |
1.1.1.145 | 3beta-hydroxy-DELTA5-steroid dehydrogenase |
adrenal gland |
isoform 3beta-hydroxysteroid dehydrogenase type 2 |
693887 |
1.1.1.145 | 3beta-hydroxy-DELTA5-steroid dehydrogenase |
adrenal gland |
isoform Hsd3b6 immunoreactivities within the adrenal gland are essentially confined to the zona glomerulosa cells, where aldosterone is produced. No immunopositive cells are observed in the zona fasciculata |
740997 |
1.1.1.145 | 3beta-hydroxy-DELTA5-steroid dehydrogenase |
adrenal gland |
isozyme 3beta-HSD2 |
662371 |
1.1.1.145 | 3beta-hydroxy-DELTA5-steroid dehydrogenase |
adrenal gland |
selectively expressed in adrenal glands and ovaries |
763397 |
1.1.1.146 | 11beta-hydroxysteroid dehydrogenase |
adrenal gland |
- |
668432, 670252, 740248 |
1.1.1.149 | 20alpha-hydroxysteroid dehydrogenase |
adrenal gland |
- |
285990 |
1.1.1.149 | 20alpha-hydroxysteroid dehydrogenase |
adrenal gland |
20alpha-HSD mRNA very low expressed |
285997 |
1.1.1.149 | 20alpha-hydroxysteroid dehydrogenase |
adrenal gland |
high expression level |
670272 |
1.1.1.149 | 20alpha-hydroxysteroid dehydrogenase |
adrenal gland |
high expression level, expression is restricted to the X-zone, adrenal 20alpha-HSD activity in male mice peaks at 3 weeks of age and disappears thereafter, whereas 20alpha-HSD enzyme activity is maintained in adrenals from nulliparous female animals |
-, 668428 |
1.1.1.149 | 20alpha-hydroxysteroid dehydrogenase |
adrenal gland |
very low expression rate of AKR1C23 |
669908 |
1.1.1.153 | sepiapterin reductase (L-erythro-7,8-dihydrobiopterin forming) |
adrenal gland |
- |
286024 |
1.1.1.153 | sepiapterin reductase (L-erythro-7,8-dihydrobiopterin forming) |
adrenal gland |
adrenal medulla |
286027 |
1.1.1.162 | erythrulose reductase |
adrenal gland |
- |
286091 |
1.1.1.188 | prostaglandin-F synthase |
adrenal gland |
- |
389464, 687797 |
1.1.1.188 | prostaglandin-F synthase |
adrenal gland |
abundant expression |
760437 |
1.1.1.21 | aldose reductase |
adrenal gland |
- |
286263, 695380, 697266 |
1.1.1.218 | morphine 6-dehydrogenase |
adrenal gland |
high expression level of AKR1C26 |
739953 |
1.1.1.218 | morphine 6-dehydrogenase |
adrenal gland |
in male hamsters |
740637 |
1.1.1.239 | 3alpha(17beta)-hydroxysteroid dehydrogenase (NAD+) |
adrenal gland |
high expression level of AKR1C26 |
739953 |
1.1.1.239 | 3alpha(17beta)-hydroxysteroid dehydrogenase (NAD+) |
adrenal gland |
in male hamsters |
740637 |
1.1.1.239 | 3alpha(17beta)-hydroxysteroid dehydrogenase (NAD+) |
adrenal gland |
in males |
287209 |
1.1.1.239 | 3alpha(17beta)-hydroxysteroid dehydrogenase (NAD+) |
adrenal gland |
predominantly expressed in the zona reticularis |
712571 |
1.1.1.270 | 3beta-hydroxysteroid 3-dehydrogenase |
adrenal gland |
- |
724124 |
1.1.1.284 | S-(hydroxymethyl)glutathione dehydrogenase |
adrenal gland |
- |
287888 |
1.1.1.315 | 11-cis-retinol dehydrogenase |
adrenal gland |
17% mRNA expression of Rdh5 compared to liver |
690797 |
1.1.1.34 | hydroxymethylglutaryl-CoA reductase (NADPH) |
adrenal gland |
- |
286564 |
1.1.1.51 | 3(or 17)beta-hydroxysteroid dehydrogenase |
adrenal gland |
- |
-, 287071, 670037, 672586 |
1.1.1.51 | 3(or 17)beta-hydroxysteroid dehydrogenase |
adrenal gland |
in female hamsters |
740637 |
1.1.1.51 | 3(or 17)beta-hydroxysteroid dehydrogenase |
adrenal gland |
isozyme 17beta-HSD5 |
675983 |
1.1.1.62 | 17beta-estradiol 17-dehydrogenase |
adrenal gland |
- |
654934, 740849 |
1.1.1.62 | 17beta-estradiol 17-dehydrogenase |
adrenal gland |
expression of type 7 17beta-hydroxysteroid dehydrogenase in zona fasciculata and reticularis in the cortex |
670031 |
1.1.1.62 | 17beta-estradiol 17-dehydrogenase |
adrenal gland |
high expression |
685803 |
1.1.1.62 | 17beta-estradiol 17-dehydrogenase |
adrenal gland |
in the three zones of the cortex, not in the medulla |
675190 |
1.1.1.62 | 17beta-estradiol 17-dehydrogenase |
adrenal gland |
low mRNA expression |
688007 |
1.1.1.64 | testosterone 17beta-dehydrogenase (NADP+) |
adrenal gland |
predominantly expressed in the zona reticularis |
712571 |
1.1.1.71 | alcohol dehydrogenase [NAD(P)+] |
adrenal gland |
- |
655563, 740291 |
1.1.1.80 | isopropanol dehydrogenase (NADP+) |
adrenal gland |
- |
287362 |
1.1.1.95 | phosphoglycerate dehydrogenase |
adrenal gland |
- |
287528 |
1.1.1.96 | diiodophenylpyruvate reductase |
adrenal gland |
- |
287552, 287554 |
1.1.1.B40 | 11beta-hydroxysteroid dehydrogenase (NAD+) |
adrenal gland |
- |
668432, 670252 |
1.11.1.12 | phospholipid-hydroperoxide glutathione peroxidase |
adrenal gland |
- |
673845 |
1.11.1.20 | prostamide/prostaglandin F2alpha synthase |
adrenal gland |
- |
687797 |
1.11.1.20 | prostamide/prostaglandin F2alpha synthase |
adrenal gland |
activity is the highest in spinal cord and brain followed by thymus, adrenal gland, heart, and genital organs |
687797 |
1.11.1.24 | thioredoxin-dependent peroxiredoxin |
adrenal gland |
less than 0.002 mg Prx I per mg of soluble protein Prx I, 0.002 mg Prx II per mg of soluble protein, less than 0.004 mg Prx III per mg of soluble protein, 0.0003 mg Prx V per mg of soluble protein and 0.0003 mg Prx VI per mg of soluble protein |
655756 |
1.11.1.9 | glutathione peroxidase |
adrenal gland |
GPx1 is highly expressed in adrenal glands |
685441 |
1.13.11.63 | beta-carotene 15,15'-dioxygenase |
adrenal gland |
- |
713952, 728342 |
1.13.11.71 | carotenoid-9',10'-cleaving dioxygenase |
adrenal gland |
- |
720152 |
1.14.11.16 | peptide-aspartate beta-dioxygenase |
adrenal gland |
- |
439251, 439254 |
1.14.13.39 | nitric-oxide synthase (NADPH) |
adrenal gland |
- |
-, 440203, 440226 |
1.14.13.39 | nitric-oxide synthase (NADPH) |
adrenal gland |
isoform I |
440226 |
1.14.14.14 | aromatase |
adrenal gland |
maternal ovaries and adrenals maintain high aromatase activity throughout gestation |
745021 |
1.14.14.154 | sterol 14alpha-demethylase |
adrenal gland |
- |
673147 |
1.14.14.16 | steroid 21-monooxygenase |
adrenal gland |
- |
285439, 285440, 285441, 285443 |
1.14.14.16 | steroid 21-monooxygenase |
adrenal gland |
sole source of enzyme expression |
659808 |
1.14.14.19 | steroid 17alpha-monooxygenase |
adrenal gland |
- |
390123, 390127, 390138, 390139, 390141, 390144, 680978, 703551, 706689 |
1.14.14.19 | steroid 17alpha-monooxygenase |
adrenal gland |
fetal and postnatal |
727367 |
1.14.14.19 | steroid 17alpha-monooxygenase |
adrenal gland |
little lyase activity |
390140 |
1.14.14.32 | 17alpha-hydroxyprogesterone deacetylase |
adrenal gland |
- |
714352, 734569 |
1.14.14.32 | 17alpha-hydroxyprogesterone deacetylase |
adrenal gland |
highest expression |
714352 |
1.14.14.79 | docosahexaenoic acid omega-hydroxylase |
adrenal gland |
- |
728344 |
1.14.15.15 | cholestanetriol 26-monooxygenase |
adrenal gland |
- |
735969, 736710 |
1.14.15.4 | steroid 11beta-monooxygenase |
adrenal gland |
- |
285386, 285406, 285407, 672590, 673348, 673923, 673954, 675052, 675053, 675684, 687021, 688009, 695555, 696010, 761755 |
1.14.15.4 | steroid 11beta-monooxygenase |
adrenal gland |
CYP11B2 |
712715 |
1.14.15.4 | steroid 11beta-monooxygenase |
adrenal gland |
zona fasciculata in the adrenal cortex |
690171 |
1.14.15.4 | steroid 11beta-monooxygenase |
adrenal gland |
zona fasiculata |
686714 |
1.14.15.4 | steroid 11beta-monooxygenase |
adrenal gland |
zona glomerulosa |
690201 |
1.14.15.6 | cholesterol monooxygenase (side-chain-cleaving) |
adrenal gland |
- |
285423, 657647, 658811, 673298, 688147 |
1.14.16.2 | tyrosine 3-monooxygenase |
adrenal gland |
- |
438655, 438685, 438686, 438693, 438697, 438698, 438706, 684899, 688508, 699662, 745891 |
1.14.16.2 | tyrosine 3-monooxygenase |
adrenal gland |
tyrosine hydroxylase in hypertensive rats shows 35% lower expression and a reduced Vmax due to a decreased phosphorylation at Ser40 |
675737 |
1.14.17.1 | dopamine beta-monooxygenase |
adrenal gland |
- |
438589, 438598, 438603, 438608, 438610, 438612, 438622, 438626, 438634, 659287, 702945, 727633 |
1.14.17.1 | dopamine beta-monooxygenase |
adrenal gland |
dietary copper deficiency is associated with increased formation of enzyme |
438636 |
1.14.99.1 | prostaglandin-endoperoxide synthase |
adrenal gland |
- |
672503 |
1.14.99.1 | prostaglandin-endoperoxide synthase |
adrenal gland |
fetal |
686417 |
1.15.1.1 | superoxide dismutase |
adrenal gland |
enzyme mRNA is only found in the inner zones of adrenal cortex, not the glomerulosa. Enzyme activity in the inner zone mitochondria is enhaced by corticotrophin and by a low-sodium diet, but suppressed by betamethasone |
675093 |
1.17.1.4 | xanthine dehydrogenase |
adrenal gland |
- |
644557, 644558 |
1.18.1.2 | ferredoxin-NADP+ reductase |
adrenal gland |
- |
285475, 285547 |
1.18.1.6 | adrenodoxin-NADP+ reductase |
adrenal gland |
- |
285476, 285480, 285521, 285528, 285555, 719773, 719775, 719777, 720222 |
1.2.1.23 | 2-oxoaldehyde dehydrogenase (NAD+) |
adrenal gland |
- |
288146 |
1.2.1.48 | long-chain-aldehyde dehydrogenase |
adrenal gland |
- |
725656 |
1.2.1.49 | 2-oxoaldehyde dehydrogenase (NADP+) |
adrenal gland |
- |
288146 |
1.2.3.1 | aldehyde oxidase |
adrenal gland |
significantly expressed |
692569 |
1.3.1.20 | trans-1,2-dihydrobenzene-1,2-diol dehydrogenase |
adrenal gland |
- |
349254 |
1.3.1.20 | trans-1,2-dihydrobenzene-1,2-diol dehydrogenase |
adrenal gland |
low activity |
349239, 349240 |
1.3.1.21 | 7-dehydrocholesterol reductase |
adrenal gland |
- |
654830 |
1.3.1.21 | 7-dehydrocholesterol reductase |
adrenal gland |
high expression level |
654193 |
1.3.1.22 | 3-oxo-5alpha-steroid 4-dehydrogenase (NADP+) |
adrenal gland |
adrenal 5alpha-reductase expression is decreased in male withdrawal seizure-prone mice |
710797 |
1.3.1.3 | DELTA4-3-oxosteroid 5beta-reductase |
adrenal gland |
- |
390593, 390646 |
1.3.1.38 | trans-2-enoyl-CoA reductase (NADPH) |
adrenal gland |
TER mRNA |
656193 |
1.3.1.48 | 13,14-dehydro-15-oxoprostaglandin 13-reductase |
adrenal gland |
- |
390826 |
1.3.1.70 | DELTA14-sterol reductase |
adrenal gland |
LBR |
672378 |
1.3.1.70 | DELTA14-sterol reductase |
adrenal gland |
TM7SF2 shows the highest mRNA expression |
672378 |
1.3.1.72 | DELTA24-sterol reductase |
adrenal gland |
- |
746354 |
1.3.3.6 | acyl-CoA oxidase |
adrenal gland |
- |
391044 |
1.3.99.5 | 3-oxo-5alpha-steroid 4-dehydrogenase (acceptor) |
adrenal gland |
abnormally high expression of isoform 2 enzyme in male and female |
662726 |