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EC 1.14.13.33 Details
show Brenda entryEC number
1.14.13.33
Accepted name
4-hydroxybenzoate 3-monooxygenase [NAD(P)H]
Reaction
4-hydroxybenzoate + NAD(P)H + H+ + O2 = 3,4-dihydroxybenzoate + NAD(P)+ + H2O
Other name(s)
4-hydroxybenzoate 3-monooxygenase (reduced nicotinamide adenine dinucleotide (phosphate)),
4-hydroxybenzoate-3-hydroxylase,
4-hydroxybenzoate 3-hydroxylase
Systematic name
4-hydroxybenzoate,NAD(P)H:oxygen oxidoreductase (3-hydroxylating)
CAS registry number
95471-33-3
Comment
A flavoprotein (FAD). The enzyme from Corynebacterium cyclohexanicum is highly specific for 4-hydroxybenzoate, but uses NADH and NADPH at approximately equal rates (cf. EC 1.14.13.2 4-hydroxybenzoate 3-monooxygenase). It is less specific for NADPH than EC 1.14.13.2.
History
created 1989, modified 1999
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1 Oxidoreductases
1.1 Acting on the CH-OH group of donors
1.4.3.9 created 1972, deleted 1984 1.4.3.17 created 2000, deleted 2003 1.4.3.18 proposed 2000 1.14.13.45 created 1992, deleted 2003
