2.5.1.26: alkylglycerone-phosphate synthase

This is an abbreviated version!
For detailed information about alkylglycerone-phosphate synthase, go to the full flat file.

Reaction

Synonyms

3-deoxy-D-arabino-heptulosonate 7-phosphate synthase, ADPS, ADS, AGPS, alkyl DHAP synthetase, alkyl dihydroxyacetone phosphate synthase, alkyl dihydroxyacetone phosphate synthetase, alkyl-DHAP, alkyl-dihydroxyacetonephosphate synthase, alkyl-dihydroxyacetonephosphate-synthase, alkyldihydroxyacetone phosphate synthase, alkyldihydroxyacetonephosphate synthase, alkyldihydroxyacetonephosphate synthetase, alkylglycerone phosphate synthase, alkylglyceronephosphate synthase, DHAP-S, synthase, alkylglycerone phosphate, synthetase, alkyldihydroxyacetone phosphate

ECTree

     2 Transferases

         2.5 Transferring alkyl or aryl groups, other than methyl groups

             2.5.1 Transferring alkyl or aryl groups, other than methyl groups (only sub-subclass identified to date)

                2.5.1.26 alkylglycerone-phosphate synthase

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Results	in table
3234	AA Sequence
6	Application
2	CAS Registry Number
11	Cloned(Commentary)
3	Cofactor
131	Disease/ Diagnostics
4	Expression
21	General Information
2	General Stability
19	Inhibitors
11	KM Value [mM]
25	Localization
5	Molecular Weight [Da]
6	Natural Substrates/ Products (Substrates)
43	Organism
3	Pathway
40	PDB ID
6	pH Optimum
1	pH Range
1	Posttranslational Modification
10	Protein Variants
8	Purification (Commentary)
8	Reaction
1	Reaction Type
43	Reference
39	Source Tissue
5	Specific Activity [micromol/min/mg]
3	Storage Stability
32	Substrates and Products (Substrate)
5	Subunits
38	Synonyms
1	Systematic Name
3	Temperature Optimum [°C]

Expression

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Expression on EC 2.5.1.26 - alkylglycerone-phosphate synthase

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EXPRESSION

ORGANISM

UNIPROT

LITERATURE

downregulation of alkylglycerone phosphate synthase and circRNAs expression has a significant effect on the regulation of biological functions, including cell adhesion, cell cycle and metabolism in various tumor types

Homo sapiens

O00116

759876

the amyloid precursor protein intracellular domain increases the expression of the alkyl-dihydroxyacetonephosphate-synthase in vivo and in vitro

Homo sapiens

-

723024

the enzyme is upregulated in multiple types of cancer cells and primary tumors

Homo sapiens

O00116

737578

up-regulated across different types of aggressive cancers such as human breast 231MFP, melanoma C8161, and prostate PC-3 cancers

Homo sapiens

O00116

759149