2.5.1.26: alkylglycerone-phosphate synthase

This is an abbreviated version!
For detailed information about alkylglycerone-phosphate synthase, go to the full flat file.

Word Map on EC 2.5.1.26

2.5.1.26

ether

shikimate

dah7ps

chorismate

plasmalogens

chondrodysplasia

rhizomelic

punctata

zellweger

prephenate

phenylalanine-sensitive

dhap-at

4.1.2.15

tyrosine-sensitive

8-phosphate

hexadecanol

5-enolpyruvylshikimate

d-erythrose

tryptophan-sensitive

plasmalogen-deficient

medicine

dihydroxyacetone-phosphate

pharmacology

Reaction

Synonyms

3-deoxy-D-arabino-heptulosonate 7-phosphate synthase, ADPS, ADS, AGPS, alkyl DHAP synthetase, alkyl dihydroxyacetone phosphate synthase, alkyl dihydroxyacetone phosphate synthetase, alkyl-DHAP, alkyl-dihydroxyacetonephosphate synthase, alkyl-dihydroxyacetonephosphate-synthase, alkyldihydroxyacetone phosphate synthase, alkyldihydroxyacetonephosphate synthase, alkyldihydroxyacetonephosphate synthetase, alkylglycerone phosphate synthase, alkylglyceronephosphate synthase, DHAP-S, synthase, alkylglycerone phosphate, synthetase, alkyldihydroxyacetone phosphate

ECTree

2 Transferases

2.5 Transferring alkyl or aryl groups, other than methyl groups

2.5.1 Transferring alkyl or aryl groups, other than methyl groups (only sub-subclass identified to date)

2.5.1.26 alkylglycerone-phosphate synthase

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Results	in table
3234	AA Sequence
6	Application
2	CAS Registry Number
11	Cloned(Commentary)
3	Cofactor
131	Disease/ Diagnostics
4	Expression
21	General Information
2	General Stability
19	Inhibitors
11	KM Value [mM]
25	Localization
5	Molecular Weight [Da]
6	Natural Substrates/ Products (Substrates)
43	Organism
3	Pathway
40	PDB ID
6	pH Optimum
1	pH Range
1	Posttranslational Modification
10	Protein Variants
8	Purification (Commentary)
8	Reaction
1	Reaction Type
43	Reference
39	Source Tissue
5	Specific Activity [micromol/min/mg]
3	Storage Stability
32	Substrates and Products (Substrate)
5	Subunits
38	Synonyms
1	Systematic Name
3	Temperature Optimum [°C]

Inhibitors

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Inhibitors on EC 2.5.1.26 - alkylglycerone-phosphate synthase

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(3S)-3-(2-fluorophenyl)-N-((2-oxo-2,3-dihydro-1H-benzo[d]imidazol-5-yl)methyl)butanamide

2 entries

2,4-dinitrofluorobenzene

Cavia porcellus

1 mM, 2% activity

489889

2-oxo-3-(phosphonooxy)propyl hexadecanoate

Trypanosoma brucei

O97157

inhibitory above 0.1 mM

489891

3-(2,6-difluorophenyl)-N-((2-oxo-2,3-dihydro-1H-benzo[d]imidazol-5-yl)methyl)butanamide

2 entries

3-Bromo-2-oxoheptadecyl phosphate

Cavia porcellus

489882

acyldihydroxyacetone phosphate

Mus musculus

high concentration, substrate inhibition

fatty acids

hexadecanol

inhibitory above 0.3 mM

Mg2+

5 mM, 70% activity

Mn2+

5 mM, 6% activity

N-ethylmaleimide

5 mM, 15% activity

NaCl

50% inhibition at 0.6 M

489891

p-bromophenacylbromide

1 mM, 55% activity

Phenylglyoxal

inactivation

Zn2+

5 mM, 8% activity

additional information

Cavia porcellus

not inhibitory: Ca2+

489889