2.3.1.253: phloroglucinol synthase
This is an abbreviated version!
For detailed information about phloroglucinol synthase, go to the full flat file.
Reaction
3 malonyl-CoA = + 3 CO2 + 3 CoA
Synonyms
PhlD, phloroglucinol synthase, type III polyketide synthase
ECTree
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Reference
Reference on EC 2.3.1.253 - phloroglucinol synthase
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Cao, Y.; Jiang, X.; Zhang, R.; Xian, M.
Improved phloroglucinol production by metabolically engineered Escherichia coli
Appl. Microbiol. Biotechnol.
91
1545-1552
2011
Pseudomonas fluorescens, Pseudomonas fluorescens Pf-5
Rao, G.; Lee, J.K.; Zhao, H.
Directed evolution of phloroglucinol synthase PhlD with increased stability for phloroglucinol production
Appl. Microbiol. Biotechnol.
97
5861-5867
2013
Pseudomonas fluorescens, Pseudomonas fluorescens Pf-5
Achkar, J.; Xian, M.; Zhao, H.; Frost, J.W.
Biosynthesis of phloroglucinol
J. Am. Chem. Soc.
127
5332-5333
2005
Pseudomonas fluorescens, Pseudomonas fluorescens Pf-5
Bangera, M.G.; Thomashow, L.S.
Identification and characterization of a gene cluster for synthesis of the polyketide antibiotic 2,4-diacetylphloroglucinol from Pseudomonas fluorescens Q2-87
J. Bacteriol.
181
3155-3163
1999
Pseudomonas fluorescens, Pseudomonas fluorescens Q2-87
Zha, W.; Rubin-Pitel, S.B.; Zhao, H.
Characterization of the substrate specificity of PhlD, a type III polyketide synthase from Pseudomonas fluorescens
J. Biol. Chem.
281
32036-32047
2006
Pseudomonas fluorescens (Q4K418), Pseudomonas fluorescens Pf-5 (Q4K418)
Zha, W.; Rubin-Pitel, S.B.; Zhao, H.
Exploiting genetic diversity by directed evolution: molecular breeding of type III polyketide synthases improves productivity
Mol. Biosyst.
4
246-248
2008
Pseudomonas fluorescens (Q4K418), Pseudomonas fluorescens Pf-5 (Q4K418)
Ramette, A.; Moenne-Loccoz, Y.; Defago, G.
Polymorphism of the polyketide synthase gene phID in biocontrol fluorescent pseudomonads producing 2,4-diacetylphloroglucinol and comparison of PhID with plant polyketide synthases
Mol. Plant Microbe Interact.
14
639-652
2001
Pseudomonas fluorescens (Q9REL4), Pseudomonas fluorescens (Q9REL5), Pseudomonas fluorescens (Q9REM4), Pseudomonas fluorescens (Q9REZ8), Pseudomonas fluorescens (Q9REZ9), Pseudomonas fluorescens Pf-5 (Q9REL4), Pseudomonas fluorescens UP61 (Q9REM4), Pseudomonas fluorescens Q8r1-96 (Q9REZ8), Pseudomonas fluorescens M1-96 (Q9REZ9), Pseudomonas fluorescens CHA0 (Q9REL5)
Zhang, R.; Liu, W.; Cao, Y.; Xu, X.; Xian, M.; Liu, H.
An in vitro synthetic biosystem based on acetate for production of phloroglucinol
BMC Biotechnol.
17
66
2017
Pseudomonas fluorescens (Q4K418), Pseudomonas fluorescens Pf-5 (Q4K418), Pseudomonas fluorescens ATCC BAA-477 (Q4K418), Pseudomonas fluorescens NRRL B-23932 (Q4K418)
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