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1.17.99.9: heme a synthase

This is an abbreviated version!
For detailed information about heme a synthase, go to the full flat file.

Word Map on EC 1.17.99.9

Reaction

ferroheme i
+
H2O
+
acceptor
=
hydroxyferroheme i
+
reduced acceptor

Synonyms

ape1694, cCtaA, COX15, COX15p, ctaA, CtaA protein, HAS, TcCox15

ECTree

     1 Oxidoreductases
         1.17 Acting on CH or CH2 groups
             1.17.99 With unknown physiological acceptors
                1.17.99.9 heme a synthase

Expression

Expression on EC 1.17.99.9 - heme a synthase

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EXPRESSION
ORGANISM
UNIPROT
LITERATURE
transcription of COX15 is positively regulated by by Hap1, a transcription factor whose activity is positively controlled by intracellular heme concentration. While COX15 mRNA levels increase with increasing intracellular heme levels in the presence of Hap1, the mRNA levels of COX15 are depressed and independent of intracellular heme levels in the absence of Hap1