2.3.1.255: N-terminal amino-acid Nalpha-acetyltransferase NatA
This is an abbreviated version!
For detailed information about N-terminal amino-acid Nalpha-acetyltransferase NatA, go to the full flat file.
Word Map on EC 2.3.1.255
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2.3.1.255
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auxiliary
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n-acetyltransferase
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n-termini
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ogden
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co-translationally
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n-alpha-acetylation
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hypk
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cotranslation
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medicine
- 2.3.1.255
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auxiliary
- n-acetyltransferase
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n-termini
-
ogden
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co-translationally
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n-alpha-acetylation
- hypk
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cotranslation
- medicine
Reaction
Synonyms
ARD homolog a, ARD1, ARD1-NAT1 Nalpha-acetyltransferase, ARD1131, ARD1198, ARD1225, ARD1235, Ard1b, ARD1p, ARD2, arrest defective 1, arrest-defective protein 1, arrest-defective protein 1 homologue, AtNAA10, daf-31, DXS707, EC 2.3.1.88, hARD1, hNaa10, hNaa15, hNaa16p, hNat2, More, MtRimI, MUSE6, N(alpha)-acetyltransferase 10, N-alpha-acetyltransferase, N-alpha-acetyltransferase 10, N-alpha-acetyltransferase 11, N-alpha-acetyltransferase 15, N-terminal acetyltransferase, N-terminal acetyltransferase 10, N-terminal acetyltransferase A, N-terminal protein acetyltransferase, NAA10, NAA10-NAA15, NAA10-NAA15 complex, NAA10-NAA15 protein complex, NAA10/ARD1, NAA11, NAA15, Nalpha-acetyltransferase, Nalpha-acetyltransferase 10, NAT, NAT1, NatA, NatA acetyltransferase, NatA Nalpha-terminal acetyltransferase, NatA protein complex, NatA protein Nalpha-terminal-acetyltransferase complex, RimI, RimI acetyltransferase, Rv3420c, SCNaa15, ScNatA, SpNaa10, SpNaa15, SSO0209, Ta0058, Ta1140, TbARD1, TcNatA, TE2, vnc, yNaa10, yNaa15, zNaa10
ECTree
2.3.1.255 N-terminal amino-acid Nalpha-acetyltransferase NatAAdvanced search results
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Source Tissue on EC 2.3.1.255 - N-terminal amino-acid Nalpha-acetyltransferase NatA
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SOURCE TISSUE 
ORGANISM
UNIPROT
COMMENTARY 
LITERATURE
SOURCE
NAA10 expression decreases with the induction of differentiation in NB4 cells, but the level of NAA11 remains unchanged
higher NAA10 transcripts in metastatic osteosarcoma tissues compared to non-metastatic tissues. MMP-2 expression levels are also significantly correlated with Naa10p levels in osteosarcoma tissues
additional information
during brain development in mouse, Naa10 and Naa15 (the auxiliary subunit of NatA) are highly expressed in regions rich in proliferating and migrating cells, such as the ventricular zone, neocortex, olfactory bulb, and hippocampus. The expression of both genes is downregulated as neurons differentiate and mitotic and migratory activities subside. Then, once again, their expression increases during postnatal development in the hippocampus and during the neuronal dendritic development of Purkinje cells (PCs) in the cerebellum. This finding indicates that the regulation of expression of both genes is related to neuronal development, especially in the hippocampus and in the PCs of the cerebellum
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during brain development in mouse, Naa10 and Naa15 (the auxiliary subunit of NatA) are highly expressed in regions rich in proliferating and migrating cells, such as the ventricular zone, neocortex, olfactory bulb, and hippocampus. The expression of both genes is downregulated as neurons differentiate and mitotic and migratory activities subside. Then, once again, their expression increases during postnatal development in the hippocampus and during the neuronal dendritic development of Purkinje cells (PCs) in the cerebellum. This finding indicates that the regulation of expression of both genes is related to neuronal development, especially in the hippocampus and in the PCs of the cerebellum
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NAA11, a homologue of NAA10, is predominantly expressed in mouse testis
NAA11, a homologue of NAA10, is predominantly expressed in mouse testis. NAA10 and NAA11 display opposite expression patterns during spermatogenesis
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NAA11, a homologue of NAA10, is predominantly expressed in mouse testis
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additional information
ubiquitous expression with especially strong staining in brain and eye
additional information
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ubiquitous expression with especially strong staining in brain and eye
additional information
enzyme levels in different osteosarcoma cell lines, overview
additional information
tissue-specific expression of Naa10 during different developmental stages in humans
additional information
NAA10 and NAA11 display opposite expression patterns during spermatogenesis. No expression of Naa11 in premeiotic spermatogonia
additional information
NAA10 and NAA11 display opposite expression patterns during spermatogenesis. No expression of Naa11 in premeiotic spermatogonia
additional information
tissue-specific expression of Naa10 during different developmental stages in C57BL6/J mice
additional information
tissue-specific expression of Naa10 during different developmental stages in C57BL6/J mice
additional information
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NAA10 and NAA11 display opposite expression patterns during spermatogenesis. No expression of Naa11 in premeiotic spermatogonia
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additional information
Q4DSU6; Q4D0P4
the subunits forming the NatA enzyme complex, TcNaa10/TcNaa15, are expressed in the three main life cycle stages of the parasite, form stable complexes in vivo, and partially cosediment with the ribosome in agreement with a cotranslational function. Expression analysis of TcNaa10/TcNaa15 in the parasite
additional information
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the subunits forming the NatA enzyme complex, TcNaa10/TcNaa15, are expressed in the three main life cycle stages of the parasite, form stable complexes in vivo, and partially cosediment with the ribosome in agreement with a cotranslational function. Expression analysis of TcNaa10/TcNaa15 in the parasite
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