2.3.1.255: N-terminal amino-acid Nalpha-acetyltransferase NatA This is an abbreviated version! For detailed information about N-terminal amino-acid Nalpha-acetyltransferase NatA, go to the full flat file .
Word Map on EC 2.3.1.255
Reaction
acetyl-CoA +
an N-terminal-glycyl-[protein] =
an N-terminal-Nalpha-acetyl-glycyl-[protein] +
CoA
Synonyms ARD homolog a, ARD1, ARD1-NAT1 Nalpha-acetyltransferase, ARD1131, ARD1198, ARD1225, ARD1235, Ard1b, ARD1p, ARD2, arrest defective 1, arrest-defective protein 1, arrest-defective protein 1 homologue, AtNAA10, daf-31, DXS707, EC 2.3.1.88, hARD1, hNaa10, hNaa15, hNaa16p, hNat2, More, MtRimI, MUSE6, N(alpha)-acetyltransferase 10, N-alpha-acetyltransferase, N-alpha-acetyltransferase 10, N-alpha-acetyltransferase 11, N-alpha-acetyltransferase 15, N-terminal acetyltransferase, N-terminal acetyltransferase 10, N-terminal acetyltransferase A, N-terminal protein acetyltransferase, NAA10, NAA10-NAA15, NAA10-NAA15 complex, NAA10-NAA15 protein complex, NAA10/ARD1, NAA11, NAA15, Nalpha-acetyltransferase, Nalpha-acetyltransferase 10, NAT, NAT1, NatA, NatA acetyltransferase, NatA Nalpha-terminal acetyltransferase, NatA protein complex, NatA protein Nalpha-terminal-acetyltransferase complex, RimI, RimI acetyltransferase, Rv3420c, SCNaa15, ScNatA, SpNaa10, SpNaa15, SSO0209, Ta0058, Ta1140, TbARD1, TcNatA, TE2, vnc, yNaa10, yNaa15, zNaa10
ECTree
Subunits
Subunits on EC 2.3.1.255 - N-terminal amino-acid Nalpha-acetyltransferase NatA
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x * 22000, SDS-PAGE
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x * 26000, calculated from amino acid sequence
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x * 30000, FLAG-tagged enzyme, SDS-PAGE
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consists of the subunits Nat1p, Ard1p, and Nat5p
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x * 27000 (Ard1p) + x * 99000 (Nat1p), Ard1p is the catalytic subunit, Nat1p is the auxiliary subunit
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x * 27000, Ard1p, SDS-PAGE
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x * 27000, Ard1p, SDS-PAGE
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x * 27500, subunit ARD1, calculated from amino acid sequence
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x * 27500, subunit ARD1, calculated from amino acid sequence
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dimer
Q4DSU6; Q4D0P4
the Trypanosoma cruzi Nat A protein complex consists of an Esmeraldo-like catalytic NatA complex subunit ARD1/TcNaa10 and a non-Esmeraldo-like auxilliary NatA complex subunit Nat1/TcNaa15
dimer
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the Trypanosoma cruzi Nat A protein complex consists of an Esmeraldo-like catalytic NatA complex subunit ARD1/TcNaa10 and a non-Esmeraldo-like auxilliary NatA complex subunit Nat1/TcNaa15
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heterotrimer
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heterotrimer
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Nat1p, Nat5p and a catalytic subunit, Ard1p
additional information
size-exclusion analysis reveals that most recombinant hARD1/NAA10 form oligomers over time, resulting in the loss of KAT activity. After purification, rhARD1/NAA10 mainly exists in a high oligomeric state and has only a few monomers. The NAT activity is highest for the monomeric enzyme, about 2fold higher compared to the oligomeric enzyme and about 20% higher compared to the dimeric enzyme
additional information
the NatA enzyme complex is composed of the subunits Naa10 and Naa15
additional information
the oligomeric recombinant hARD1/NAA10 loses the ability for lysine acetylation, while the monomeric form clearly shows lysine acetylation activity in vitro
additional information
secondary structure prediction of MtRimI, overview
additional information
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secondary structure prediction of MtRimI, overview
additional information
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secondary structure prediction of MtRimI, overview
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additional information
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secondary structure prediction of MtRimI, overview
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additional information
the NatA enzyme complex is composed of the subunits Naa10 and Naa15
additional information
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the NatA enzyme complex is composed of the subunits Naa10 and Naa15
additional information
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the NatA enzyme complex is composed of the subunits Naa10 and Naa15
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additional information
the NatA enzyme complex is composed of the subunits Naa10 and Naa15
additional information
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the NatA enzyme complex is composed of the subunits Naa10 and Naa15
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additional information
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the NatA enzyme complex is composed of the subunits Naa10 and Naa15
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