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Literature summary for 2.3.1.255 extracted from

  • Arnesen, T.; Gromyko, D.; Kagabo, D.; Betts, M.; Starheim, K.; Varhaug, J.; Anderson, D.; Lillehaug, J.
    A novel human NatA Nα-terminal acetyltransferase complex: HNaa16p-hNaa10p (hNat2-hArd1) (2009), BMC Biochem., 10, 15.
    View publication on PubMedView publication on EuropePMC
Search for more literature for 2.3.1.255

Cloned(Commentary)

Cloned (Comment) Organism
a plasmid expressing hNaa16p, NARG1L-FLAG, is used Homo sapiens

Inhibitors

Inhibitors Comment Organism Structure
siRNA
-
 Homo sapiens

Localization

Localization Comment Organism GeneOntology No. Textmining
ribosome
-
 Homo sapiens 5840
-

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
acetyl-CoA + peptide Homo sapiens
-
 Nalpha-acetylpeptide + CoA
-
 ?

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Purification (Commentary)

Purification (Comment) Organism
ribosomes of HEK-293 cells are isolated Homo sapiens

Source Tissue

Source Tissue Comment Organism Textmining
8305C cell
-
 Homo sapiens
-
A-431 cell
-
 Homo sapiens
-
ARO cell
-
 Homo sapiens
-
B-CPAP cell
-
 Homo sapiens
-
BHT-101 cell
-
 Homo sapiens
-
CAL-62 cell
-
 Homo sapiens
-
CGTH-W1 cell
-
 Homo sapiens
-
GaMG cell
-
 Homo sapiens
-
HCT-116 cell
-
 Homo sapiens
-
HEK-293 cell
-
 Homo sapiens
-
HeLa cell
-
 Homo sapiens
-
Hep-G2 cell
-
 Homo sapiens
-
MCF-7 cell
-
 Homo sapiens
-
NCI-H1299 cell
-
 Homo sapiens
-
NPA cell
-
 Homo sapiens
-
Nthy-ori 3-1 cell
-
 Homo sapiens
-
ONCO-DG1 cell
-
 Homo sapiens
-
SK-MEL-2 cell
-
 Homo sapiens
-
SK-N-MC cell
-
 Homo sapiens
-
TAD-2 cell
-
 Homo sapiens
-
thyroid gland
-
 Homo sapiens
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
acetyl-CoA + peptide
-
 Homo sapiens Nalpha-acetylpeptide + CoA
-
 ?

Synonyms

Synonyms Comment Organism
hNaa16p
-
 Homo sapiens
hNat2
-
 Homo sapiens
NatA Nalpha-terminal acetyltransferase
-
 Homo sapiens

Temperature Optimum [°C]

Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
37
-
 acetylation assay Homo sapiens

pH Optimum

pH Optimum Minimum pH Optimum Maximum Comment Organism
8.5
-
 acetylation assay Homo sapiens

Cofactor

Cofactor Comment Organism Structure
acetyl-CoA
-
 Homo sapiens