EC Explorer

1.14.19.32

palmitoyl-CoA 14-(E/Z)-desaturase

(1) palmitoyl-CoA + 2 ferrocytochrome b₅ + O₂ + 2 H⁺ = (14E)-hexadec-14-enoyl-CoA + 2 ferricytochrome b₅ + 2 H₂O;;(2) palmitoyl-CoA + 2 ferrocytochrome b₅ + O₂ + 2 H⁺ = (14Z)-hexadec-14-enoyl-CoA + 2 ferricytochrome b₅ + 2 H₂O

palmitoyl-CoA,ferrocytochrome b₅:oxygen oxidoreductase (14,15 cis/trans-dehydrogenating)

The enzyme, found in the moth Ostrinia furnacalis (Asian corn borer), produces a mixture of (E)- and (Z)- isomers. The products are subsequently truncated by partial β-oxidation to a blend of 12(E/Z)-tetradec-12-enoyl-CoA, which are converted to the species-specific sex pheromones (E)- and (Z)-tetradec-12-enoyl acetates.

created 2015