2.5.1.B41: trifunctional (all-E)-isoprenyl diphospate synthase
This is an abbreviated version!
For detailed information about trifunctional (all-E)-isoprenyl diphospate synthase, go to the full flat file.
Reaction
Synonyms
(all-E)-isoprenyl diphosphate synthase, E-IDS2-L, E-IDS2-S, geranylfarnesyl diphosphate/hexaprenyl diphosphate/heptaprenyl diphosphate synthase, GFPP/HexPP/HepPP synthase, HepS, HepT
ECTree
2.5.1.B41 trifunctional (all-E)-isoprenyl diphospate synthaseAdvanced search results
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Substrates Products on EC 2.5.1.B41 - trifunctional (all-E)-isoprenyl diphospate synthase
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SUBSTRATE 
PRODUCT
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate)
(Substrate)
LITERATURE
(Substrate)
(Substrate)
COMMENTARY
(Product)
(Product)
LITERATURE
(Product)
(Product)
Reversibility
r=reversible
ir=irreversible
?=not specified
r=reversible
ir=irreversible
?=not specified
(2E,6E)-farnesyl diphosphate + 4 isopentenyl diphosphate
4 diphosphate + all-trans-heptaprenyl diphosphate
geranylgeranyl diphosphate + 2 isopentenyl diphosphate
2 diphosphate + all-trans-hexaprenyl diphosphate
geranylgeranyl diphosphate + isopentenyl diphosphate
(2E,6E,10E,14E)-geranylfarnesyl diphosphate + diphosphate
heterodimeric E-IDS (HepS/T), cf. EC 2.5.1.81
-
-
?
(2E,6E)-farnesyl diphosphate + 4 isopentenyl diphosphate
4 diphosphate + all-trans-heptaprenyl diphosphate
heptaprenyl diphosphate is biosynthesized from isopentenyl diphosphate and farnesyl diphosphate by heterodimeric E-IDS (HepS/T), cf. EC 2.5.1.30, low activity
-
-
?
(2E,6E)-farnesyl diphosphate + 4 isopentenyl diphosphate
4 diphosphate + all-trans-heptaprenyl diphosphate
heptaprenyl diphosphate is biosynthesized from isopentenyl diphosphate and farnesyl diphosphate by heterodimeric E-IDS (HepS/T), cf. EC 2.5.1.30
-
-
?
(2E,6E)-farnesyl diphosphate + 4 isopentenyl diphosphate
4 diphosphate + all-trans-heptaprenyl diphosphate
Alkalihalobacillus clausii JCM 9138
heptaprenyl diphosphate is biosynthesized from isopentenyl diphosphate and farnesyl diphosphate by heterodimeric E-IDS (HepS/T), cf. EC 2.5.1.30, low activity
-
-
?
(2E,6E)-farnesyl diphosphate + 4 isopentenyl diphosphate
4 diphosphate + all-trans-heptaprenyl diphosphate
Alkalihalobacillus clausii JCM 9138
heptaprenyl diphosphate is biosynthesized from isopentenyl diphosphate and farnesyl diphosphate by heterodimeric E-IDS (HepS/T), cf. EC 2.5.1.30
-
-
?
geranylgeranyl diphosphate + 2 isopentenyl diphosphate
2 diphosphate + all-trans-hexaprenyl diphosphate
heterodimeric E-IDS (HepS/T), cf. EC 2.5.1.82
-
-
?
geranylgeranyl diphosphate + 2 isopentenyl diphosphate
2 diphosphate + all-trans-hexaprenyl diphosphate
Alkalihalobacillus clausii JCM 9138
heterodimeric E-IDS (HepS/T), cf. EC 2.5.1.82
-
-
?
additional information
?
-
formation of geranylfarnesyl diphosphate and hexaprenyl diphosphate is mediated by heteromeric E-IDS2-S/L. E-IDS2-S or E-IDS2-L alone form no product from dimethylallyl diphosphate, (2E,6E)-farnesyl diphosphate, and geranylgeranyl diphosphate
-
-
?
additional information
?
-
formation of geranylfarnesyl diphosphate and hexaprenyl diphosphate is mediated by heteromeric E-IDS2-S/L. E-IDS2-S or E-IDS2-L alone form no product from dimethylallyl diphosphate, (2E,6E)-farnesyl diphosphate, and geranylgeranyl diphosphate
-
-
?
additional information
?
-
-
formation of geranylfarnesyl diphosphate and hexaprenyl diphosphate is mediated by heteromeric E-IDS2-S/L. E-IDS2-S or E-IDS2-L alone form no product from dimethylallyl diphosphate, (2E,6E)-farnesyl diphosphate, and geranylgeranyl diphosphate
-
-
?
additional information
?
-
product identification and determination by mass spectrometry, NMR spectrometry, and TLC
-
-
?
additional information
?
-
product identification and determination by mass spectrometry, NMR spectrometry, and TLC
-
-
?
additional information
?
-
-
product identification and determination by mass spectrometry, NMR spectrometry, and TLC
-
-
?
additional information
?
-
Alkalihalobacillus clausii JCM 9138
formation of geranylfarnesyl diphosphate and hexaprenyl diphosphate is mediated by heteromeric E-IDS2-S/L. E-IDS2-S or E-IDS2-L alone form no product from dimethylallyl diphosphate, (2E,6E)-farnesyl diphosphate, and geranylgeranyl diphosphate
-
-
?
additional information
?
-
Alkalihalobacillus clausii JCM 9138
formation of geranylfarnesyl diphosphate and hexaprenyl diphosphate is mediated by heteromeric E-IDS2-S/L. E-IDS2-S or E-IDS2-L alone form no product from dimethylallyl diphosphate, (2E,6E)-farnesyl diphosphate, and geranylgeranyl diphosphate
-
-
?
additional information
?
-
Alkalihalobacillus clausii JCM 9138
product identification and determination by mass spectrometry, NMR spectrometry, and TLC
-
-
?
additional information
?
-
Alkalihalobacillus clausii JCM 9138
product identification and determination by mass spectrometry, NMR spectrometry, and TLC
-
-
?
