2.3.1.85: fatty-acid synthase system
This is an abbreviated version!
For detailed information about fatty-acid synthase system, go to the full flat file.
Word Map on EC 2.3.1.85
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2.3.1.85
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mycobacterium
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tuberculosis
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mycolic
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lipogenic
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enoyl
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fasciclin
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cerulenin
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beta-ketoacyl-acyl
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malonyl-coa
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triclosan
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isoniazid
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transacylase
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enoyl-acyl
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beta-ketoacyl
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thiolactomycin
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malonyl-acp
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condensing
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acyl-acps
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malonyl
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srebp-1c
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fabgs
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medicine
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apicoplast
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boutons
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phosphopantetheinylation
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4'-phosphopantetheine
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ketoacyl
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antituberculous
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thiacetazone
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nutrition
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analysis
- 2.3.1.85
- mycobacterium
- tuberculosis
-
mycolic
-
lipogenic
-
enoyl
-
fasciclin
- cerulenin
-
beta-ketoacyl-acyl
- malonyl-coa
- triclosan
- isoniazid
-
transacylase
-
enoyl-acyl
-
beta-ketoacyl
- thiolactomycin
- malonyl-acp
-
condensing
- acyl-acps
-
malonyl
- srebp-1c
-
fabgs
- medicine
- apicoplast
-
boutons
-
phosphopantetheinylation
- 4'-phosphopantetheine
-
ketoacyl
-
antituberculous
- thiacetazone
- nutrition
- analysis
Reaction
+ 7 malonyl-CoA + 14 NADPH + 14 H+ = + 8 CoA + 7 CO2 + 14 NADP+ + 6 H2O
Synonyms
F09E10.3 protein, FAS, FAS-II, FASI, FASII, FASN, fatty acid synthase, fatty acid synthase I, fatty acid synthase II, fatty acid synthase type 2, fatty-acid synthase, type 2 dissociative FAS, type 2 fatty acid synthase, type II fatty acid synthase, yeast fatty acid synthase
ECTree
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IC50 Value
IC50 Value on EC 2.3.1.85 - fatty-acid synthase system
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0.0254
1,1'-[methanediylbis(2,4,6-trihydroxy-5-methylbenzene-3,1-diyl)]dibutan-1-one
Gallus gallus
-
IC50: 0.0254 mM
0.0016
1,2,3,4,6-penta-O-galloyl-beta-D-glucose
Homo sapiens
-
37°C, pH not specified in the publication
0.0602
2,2'-methanediylbis(3,5-dihydroxy-4,4-dimethyl-6-propanoylcyclohexa-2,5-dien-1-one)
Gallus gallus
-
IC50: 0.0602 mM
0.0231
2-(3-butanoyl-2,4,6-trihydroxy-5-methylbenzyl)-3,5-dihydroxy-4,4-dimethyl-6-propanoylcyclohexa-2,5-dien-1-one
Gallus gallus
-
IC50: 0.0231 mM
0.0287
2-acetyl-6-(3-butanoyl-2,4,6-trihydroxy-5-methylbenzyl)-3,5-dihydroxy-4,4-dimethylcyclohexa-2,5-dien-1-one
Gallus gallus
-
IC50: 0.0287 mM
0.0297
2-acetyl-6-(3-butanoyl-2,4,6-trihydroxybenzyl)-3,5-dihydroxy-4,4-dimethylcyclohexa-2,5-dien-1-one
Gallus gallus
-
IC50: 0.0297 mM
0.0717
2-acetyl-6-[(2,4-dihydroxy-3,3-dimethyl-6-oxo-5-propanoylcyclohexa-1,4-dien-1-yl)methyl]-3,5-dihydroxy-4,4-dimethylcyclohexa-2,5-dien-1-one
Gallus gallus
-
IC50: 0.0717 mM
0.031
2-acetyl-6-{3-butanoyl-5-[(2,4-dihydroxy-3,3-dimethyl-6-oxo-5-propanoylcyclohexa-1,4-dien-1-yl)methyl]-2,4,6-trihydroxybenzyl}-3,5-dihydroxy-4,4-dimethylcyclohexa-2,5-dien-1-one
Gallus gallus
-
IC50: 0.031 mM
0.0326
2-butanoyl-6-(3-butanoyl-2,6-dihydroxy-4-methoxy-5-methylbenzyl)-3,5-dihydroxy-4,4-dimethylcyclohexa-2,5-dien-1-one
Gallus gallus
-
IC50: 0.0326 mM
0.0561
2-butanoyl-6-[(2,4-dihydroxy-3,3-dimethyl-6-oxo-5-propanoylcyclohexa-1,4-dien-1-yl)methyl]-3,5-dihydroxy-4,4-dimethylcyclohexa-2,5-dien-1-one
Gallus gallus
-
IC50: 0.0561 mM
0.0127
2-[(Z)-[2-[4-(3-nitrophenyl)-1,3-thiazol-2-yl]hydrazinylidene]methyl]pyridine
Homo sapiens
pH not specified in the publication, temperature not specified in the publication
0.093
nordihydroguaiaretic acid
Anas platyrhynchos
-
inhibits competitively with respect to acetyl-CoA, noncompetitively with respect to malonyl-CoA, and in a mixed manner with respect toNADPH.IC50 = 0.093 mM
additional information
Gallus gallus
-
IC50 value is 4.61 microg/ml, pH 7.0, 37°C
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additional information
procyanidin
Homo sapiens
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IC50 value is 0.087 microg/ml, 37°C, pH not specified in the publication
additional information
resveratrol
Gallus gallus
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IC50 value is 11.1 microg/ml, pH 7.0, 37°C