2.1.1.B74: apigenin 7-O-methyltransferase
This is an abbreviated version!
For detailed information about apigenin 7-O-methyltransferase, go to the full flat file.
Reaction
Synonyms
F1-OMT, F7OMT, flavone 7-O-methyltransferase, flavonoid 7-O-methyltransferase, flavonoid 7-OMT, POMT-7, POMT7
ECTree
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Application
Application on EC 2.1.1.B74 - apigenin 7-O-methyltransferase
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synthesis
expression together with basil flavonoid 6-hydroxylase encoded by CYP82D33 and further ethyltransferases in Saccharomyces cerevisiae to produce 8- and/or 6-substituted, methoxylated flavones from their natural precursor apigenin. The yeast cells produce substantial amounts of 6-hydroxylated, methylated derivatives of naringenin and luteolin while the corresponding derivatives of flavonol kaempferol are only detected in trace amounts. The substrate specificity of both the hydroxylases and the flavonoid O-methyltransferases is limiting yields obtained with alternative substrates