2.1.1.366: [histone H3]-N6,N6-dimethyl-lysine9 N-methyltransferase
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For detailed information about [histone H3]-N6,N6-dimethyl-lysine9 N-methyltransferase, go to the full flat file.
Reaction
Synonyms
ERG-associated protein with SET domain, ESET, KIAA0067, KMT1E, SETDB1
ECTree
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Localization
Localization on EC 2.1.1.366 - [histone H3]-N6,N6-dimethyl-lysine9 N-methyltransferase
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expression is observed mainly in the cytoplasm of various human cell lines
combined treatment with the nuclear export inhibitor leptomycin B and the proteasome inhibitor MG132 leads to the accumulation of SETDB1 in the nucleus