1.14.99.69: tRNA 2-(methylsulfanyl)-N6-isopentenyladenosine37 hydroxylase
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For detailed information about tRNA 2-(methylsulfanyl)-N6-isopentenyladenosine37 hydroxylase, go to the full flat file.
Reaction
Synonyms
miaE, PP2188, tRNA 2-(methylsulfanyl)-N6-dimethylallyladenosine37 hydroxylase, tRNA 2-methylthio-N6-isopentenyl adenosine(37) hydroxylase
ECTree
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Systematic Name
Systematic Name on EC 1.14.99.69 - tRNA 2-(methylsulfanyl)-N6-isopentenyladenosine37 hydroxylase
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tRNA N6-(3-methylbut-2-en-1-yl)-2-(methylsulfanyl)adenosine37,donor:oxygen 4-oxidoreductase (trans-hydroxylating)
The enzyme, found only within a small subset of facultative anaerobic bacteria, belongs to the nonheme diiron family. The enzyme from Salmonella typhimurium was shown to catalyse a stereoselective (E)-hydroxylation at the terminal C4-position of the prenyl group.