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1.14.99.69: tRNA 2-(methylsulfanyl)-N6-isopentenyladenosine37 hydroxylase

This is an abbreviated version!
For detailed information about tRNA 2-(methylsulfanyl)-N6-isopentenyladenosine37 hydroxylase, go to the full flat file.

Reaction

N6-(3-methylbut-2-en-1-yl)-2-(methylsulfanyl)adenosine37 in tRNA
+
reduced acceptor
+
O2
=
N6-[(2E)-4-hydroxy-3-methylbut-2-en-1-yl]-2-(methylsulfanyl)adenosine37 in tRNA
+
acceptor
+
H2O

Synonyms

miaE, PP2188, tRNA 2-(methylsulfanyl)-N6-dimethylallyladenosine37 hydroxylase, tRNA 2-methylthio-N6-isopentenyl adenosine(37) hydroxylase

ECTree

     1 Oxidoreductases
         1.14 Acting on paired donors, with incorporation or reduction of molecular oxygen
             1.14.99 Miscellaneous
                1.14.99.69 tRNA 2-(methylsulfanyl)-N6-isopentenyladenosine37 hydroxylase

Reference

Reference on EC 1.14.99.69 - tRNA 2-(methylsulfanyl)-N6-isopentenyladenosine37 hydroxylase

Please use the Reference Search for a specific query.
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REF.
AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
Corder, A.; Subedi, B.; Zhang, S.; Dark, A.; Foss Jr., F.; Pierce, B.
Peroxide-shunt substrate-specificity for the Salmonella typhimurium O 2-dependent tRNA modifying monooxygenase (MiaE)
Biochemistry
52
6182-6196
2013
Salmonella enterica subsp. enterica serovar Typhimurium (Q08015)
Manually annotated by BRENDA team
Subedi, B.; Corder, A.; Zhang, S.; Foss, F.; Pierce, B.
Steady-state kinetics and spectroscopic characterization of enzyme-tRNA interactions for the non-heme diiron tRNA-monooxygenase, MiaE
Biochemistry
54
363-376
2015
Salmonella enterica subsp. enterica serovar Typhimurium (Q08015)
Manually annotated by BRENDA team
Persson, B.; Bjork, G.
Isolation of the gene (miaE) encoding the hydroxylase involved in the synthesis of 2-methylthio-cis-ribozeatin in tRNA of Salmonella typhimurium and characterization of mutants
J. Bacteriol.
175
7776-7785
1993
Salmonella enterica subsp. enterica serovar Typhimurium (Q08015)
Manually annotated by BRENDA team
Persson, B.; Olafsson, O.; Lundgren, H.; Hederstedt, L.; Bjoerk, G.
The ms2io6A37 modification of tRNA in Salmonella typhimurium regulates growth on citric acid cycle intermediates
J. Bacteriol.
180
3144-3151
1998
Salmonella enterica subsp. enterica serovar Typhimurium (Q08015)
Manually annotated by BRENDA team
Carpentier, P.; Lepretre, C.; Basset, C.; Douki, T.; Torelli, S.; Duarte, V.; Hamdane, D.; Fontecave, M.; Atta, M.
Structural, biochemical and functional analyses of tRNA-monooxygenase enzyme MiaE from Pseudomonas putida provide insights into tRNA/MiaE interaction
Nucleic Acids Res.
48
9918-9930
2020
Pseudomonas putida (Q88KV1), Pseudomonas putida DSM6125 (Q88KV1)
Manually annotated by BRENDA team
Kaminska, K.; Baraniak, U.; Boniecki, M.; Nowaczyk, K.; Czerwoniec, A.; Bujnicki, J.
Structural bioinformatics analysis of enzymes involved in the biosynthesis pathway of the hypermodified nucleoside ms2io6A37 in tRNA
Proteins
70
1-18
2008
Salmonella enterica subsp. enterica serovar Typhimurium (Q08015)
Manually annotated by BRENDA team