1.14.20.12: 3-[(E)-2-isocyanoethenyl]-1H-indole synthase
This is an abbreviated version!
For detailed information about 3-[(E)-2-isocyanoethenyl]-1H-indole synthase, go to the full flat file.
Reaction
Synonyms
isnB
ECTree
Advanced search results
Substrates Products
Substrates Products on EC 1.14.20.12 - 3-[(E)-2-isocyanoethenyl]-1H-indole synthase
Please wait a moment until all data is loaded. This message will disappear when all data is loaded.
REACTION DIAGRAM
(2S)-3-(1H-indol-3-yl)-2-isocyanopropanoate + 2-oxoglutarate + O2
3-[(E)-2-isocyanoethenyl]-1H-indole + succinate + 2 CO2 + H2O
-
-
-
?
additional information
?
-
enzyme initiates stereoselective olefination via a benzylic C-H bond activation by an Fe(IV)-oxo intermediate, and the reaction likely proceeds through a radical- or carbocation-induced decarboxylation to complete C=C bond installation
-
-
?