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1.14.20.12: 3-[(E)-2-isocyanoethenyl]-1H-indole synthase

This is an abbreviated version!
For detailed information about 3-[(E)-2-isocyanoethenyl]-1H-indole synthase, go to the full flat file.

Reaction

(2S)-3-(1H-indol-3-yl)-2-isocyanopropanoate
+
2-oxoglutarate
+
O2
=
3-[(E)-2-isocyanoethenyl]-1H-indole
+
succinate
+ 2 CO2 +
H2O

Synonyms

isnB

ECTree

     1 Oxidoreductases
         1.14 Acting on paired donors, with incorporation or reduction of molecular oxygen
             1.14.20 With 2-oxoglutarate as one donor, and the other dehydrogenated
                1.14.20.12 3-[(E)-2-isocyanoethenyl]-1H-indole synthase

Reference

Reference on EC 1.14.20.12 - 3-[(E)-2-isocyanoethenyl]-1H-indole synthase

Please use the Reference Search for a specific query.
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REF.
AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
Brady, S.; Clardy, J.
Systematic investigation of the Escherichia coli metabolome for the biosynthetic origin of an isocyanide carbon atom
Angew. Chem. Int. Ed. Engl.
44
7045-7048
2005
uncultured organism (Q108L2)
Manually annotated by BRENDA team
Brady, S.; Clardy, J.
Cloning and heterologous expression of isocyanide biosynthetic genes from environmental DNA
Angew. Chem. Int. Ed. Engl.
44
7063-7065
2005
uncultured organism (Q108L2)
Manually annotated by BRENDA team
Huang, J.L.; Tang, Y.; Yu, C.P.; Sanyal, D.; Jia, X.; Liu, X.; Guo, Y.; Chang, W.C.
Mechanistic investigation of oxidative decarboxylation catalyzed by two iron(II)- and 2-oxoglutarate-dependent enzymes
Biochemistry
57
1838-1841
2018
uncultured organism (Q108L2)
Manually annotated by BRENDA team