1.14.19.58: tryptophan 5-halogenase
This is an abbreviated version!
For detailed information about tryptophan 5-halogenase, go to the full flat file.
Word Map on EC 1.14.19.58
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1.14.19.58
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halogenases
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flavin-dependent
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regioselective
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7-halogenase
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chlorinate
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indole
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synthesis
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albogriseolus
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biocatalysts
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brominate
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cl
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flavin
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pharmacology
- 1.14.19.58
- halogenases
-
flavin-dependent
-
regioselective
-
7-halogenase
-
chlorinate
- indole
- synthesis
- albogriseolus
-
biocatalysts
-
brominate
- cl
- flavin
- pharmacology
Reaction
Synonyms
halogenase, mibH, pyrH, sttH, trp-5-halogenase
ECTree
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Natural Substrates Products
Natural Substrates Products on EC 1.14.19.58 - tryptophan 5-halogenase
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REACTION DIAGRAM
L-tryptophan + FADH2 + Br- + O2 + H+
5-bromo-L-tryptophan + FAD + 2 H2O
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-
-
-
?
5-chloro-L-tryptophan + FAD + 2 H2O
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-
-
?
L-tryptophan + FADH2 + Cl- + O2 + H+
5-chloro-L-tryptophan + FAD + 2 H2O
-
-
-
?
L-tryptophan + FADH2 + Cl- + O2 + H+
5-chloro-L-tryptophan + FAD + 2 H2O
-
-
-
-
?
L-tryptophan + FADH2 + Cl- + O2 + H+
5-chloro-L-tryptophan + FAD + 2 H2O
pyrroindomycin biosynthesis
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-
?
L-tryptophan + FADH2 + Cl- + O2 + H+
5-chloro-L-tryptophan + FAD + 2 H2O
the enzyme is involved in the biosynthesis of the antibiotic pyrroindomycin B that contains an indole ring chlorinated in the 5 position
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-
?
L-tryptophan + FADH2 + Cl- + O2 + H+
5-chloro-L-tryptophan + FAD + 2 H2O
the enzyme is involved in the biosynthesis of the antibiotic pyrroindomycin B that contains an indole ring chlorinated in the 5 position
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-
?