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1.14.19.58: tryptophan 5-halogenase

This is an abbreviated version!
For detailed information about tryptophan 5-halogenase, go to the full flat file.

Word Map on EC 1.14.19.58

Reaction

L-tryptophan
+
FADH2
 +
chloride
 +
O2
 +
H+
=
5-chloro-L-tryptophan
 +
FAD
 + 2 H2O

Synonyms

halogenase, mibH, pyrH, sttH, trp-5-halogenase

ECTree

     1 Oxidoreductases
         1.14 Acting on paired donors, with incorporation or reduction of molecular oxygen
             1.14.19 With oxidation of a pair of donors resulting in the reduction of O2 to two molecules of water
                1.14.19.58 tryptophan 5-halogenase

Cloned

Cloned on EC 1.14.19.58 - tryptophan 5-halogenase

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CLONED (Commentary)
ORGANISM
UNIPROT
LITERATURE
expression in Arabidopsis thaliana
expression in Escherichia coli
for expression in Pseudomonas fluorescens
-
gene mibH, DNA and amino acid sequence determination and analysis, phylogenetic analysis, recombinant expression of His6-tagged enzyme in Escherichia coli, coexpression of mibH with the chaperones groES/EL and gene mibS
His-tagged apoPyrH was expressed in Pseudomonas fluorescens BL915
overexpression in Pseudomonas fluorescens BL915 DELTAORF1