1.14.18.B1: 5,6-dihydroxyindole-2-carboxylic acid oxidase
This is an abbreviated version!
For detailed information about 5,6-dihydroxyindole-2-carboxylic acid oxidase, go to the full flat file.
Word Map on EC 1.14.18.B1
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1.14.18.B1
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chromatin
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demethylases
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trimethylation
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demethylation
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gsk-j4
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polycomb
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h3k4me3
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self-renewal
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tetratricopeptide
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chip-qpcr
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zeste
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lysine-27
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lysine-specific
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containing-3
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h3k27ac
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k-specific
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polycomb-mediated
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medicine
- 1.14.18.B1
- chromatin
- demethylases
-
trimethylation
-
demethylation
- gsk-j4
-
polycomb
-
h3k4me3
-
self-renewal
-
tetratricopeptide
-
chip-qpcr
-
zeste
-
lysine-27
-
lysine-specific
-
containing-3
-
h3k27ac
-
k-specific
-
polycomb-mediated
- medicine
Reaction
Synonyms
H3K27 demethylase, H3K27me3 histone demethylase, histone demethylase, histone H3K27 demethylase, JmjC domain-containing protein 3, JMJD3, Jumonji domain-containing protein 3, KDM6B, kdm6ba, lysine demethylase 6B, PHD finger protein 8, PHF8
ECTree
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Expression
Expression on EC 1.14.18.B1 - 5,6-dihydroxyindole-2-carboxylic acid oxidase
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upregulation of histone H3K27 demethylase JMJD3 by long noncoding RNA HOTAIR, i.e. homeobox transcript antisense intergenic RNA, a kind of non-protein coding transcripts longer than 200 nucleotides. HOTAIR is an important promoter in metastasis of renal cell carcinoma and also plays a dual regulatory role in chromatin state by effecting both histone metylation and demethylation at different gene loci. HOTAIR can affect histone H3K27 methylation and its target genes' expression