1.14.15.34: 20-oxo-5-O-mycaminosyltylactone 23-monooxygenase
This is an abbreviated version!
For detailed information about 20-oxo-5-O-mycaminosyltylactone 23-monooxygenase, go to the full flat file.
Reaction
+ 2 reduced ferredoxin [iron-sulfur] cluster + 2 H+ + = + 2 oxidized ferredoxin [iron-sulfur] cluster +
Synonyms
chmH, EC 1.14.13.186, TylH, tylH1
ECTree
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Substrates Products
Substrates Products on EC 1.14.15.34 - 20-oxo-5-O-mycaminosyltylactone 23-monooxygenase
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REACTION DIAGRAM
20-oxo-5-O-beta-mycaminosyltylactone + 2 reduced ferredoxin [iron-sulfur] cluster + 2 H+ + O2
5-O-beta-mycaminosyltylonolide + 2 oxidized ferredoxin [iron-sulfur] cluster + H2O
5-O-beta-mycaminosyltylonolide + 2 oxidized ferredoxin [iron-sulfur] cluster + H2O
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20-oxo-5-O-beta-mycaminosyltylactone + 2 reduced ferredoxin [iron-sulfur] cluster + 2 H+ + O2
5-O-beta-mycaminosyltylonolide + 2 oxidized ferredoxin [iron-sulfur] cluster + H2O
the enzyme is involved in the biosynthetic pathway of the macrolide antibiotic tylosin, which is produced by several species of Streptomyces
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