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1.14.15.34: 20-oxo-5-O-mycaminosyltylactone 23-monooxygenase

This is an abbreviated version!
For detailed information about 20-oxo-5-O-mycaminosyltylactone 23-monooxygenase, go to the full flat file.

Reaction

20-oxo-5-O-beta-mycaminosyltylactone
+ 2 reduced ferredoxin [iron-sulfur] cluster + 2 H+ +
O2
=
5-O-beta-mycaminosyltylonolide
+ 2 oxidized ferredoxin [iron-sulfur] cluster +
H2O

Synonyms

chmH, EC 1.14.13.186, TylH, tylH1

ECTree

     1 Oxidoreductases
         1.14 Acting on paired donors, with incorporation or reduction of molecular oxygen
             1.14.15 With reduced iron-sulfur protein as one donor, and incorporation of one atom of oxygen into the other donor
                1.14.15.34 20-oxo-5-O-mycaminosyltylactone 23-monooxygenase

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Resultsin table
3AA Sequence
1General Information
1Natural Substrates/ Products (Substrates)
2Organism
4Pathway
1Reaction
2Reference
2Substrates and Products (Substrate)
4Synonyms
1Systematic Name

Reference

Reference on EC 1.14.15.34 - 20-oxo-5-O-mycaminosyltylactone 23-monooxygenase

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REF.
AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
Reeves, C.D.; Ward, S.L.; Revill, W.P.; Suzuki, H.; Marcus, M.; Petrakovsky, O.V.; Marquez, S.; Fu, H.; Dong, S.D.; Katz, L.
Production of hybrid 16-membered macrolides by expressing combinations of polyketide synthase genes in engineered Streptomyces fradiae hosts
Chem. Biol.
11
1465-1472
2004
Streptomyces fradiae (Q9ZHQ1)
Manually annotated by BRENDA team
Baltz, R.; Seno, E.
Properties of Streptomyces fradiae mutants blocked in biosynthesis of the macrolide antibiotic tylosin
Antimicrob. Agents Chemother.
20
214-225
1981
Streptomyces fradiae
Manually annotated by BRENDA team