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1.14.15.34: 20-oxo-5-O-mycaminosyltylactone 23-monooxygenase

This is an abbreviated version!
For detailed information about 20-oxo-5-O-mycaminosyltylactone 23-monooxygenase, go to the full flat file.

Reaction

20-oxo-5-O-beta-mycaminosyltylactone
+ 2 reduced ferredoxin [iron-sulfur] cluster + 2 H+ +
O2
=
5-O-beta-mycaminosyltylonolide
+ 2 oxidized ferredoxin [iron-sulfur] cluster +
H2O

Synonyms

chmH, EC 1.14.13.186, TylH, tylH1

ECTree

     1 Oxidoreductases
         1.14 Acting on paired donors, with incorporation or reduction of molecular oxygen
             1.14.15 With reduced iron-sulfur protein as one donor, and incorporation of one atom of oxygen into the other donor
                1.14.15.34 20-oxo-5-O-mycaminosyltylactone 23-monooxygenase

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Resultsin table
3AA Sequence
1General Information
1Natural Substrates/ Products (Substrates)
2Organism
4Pathway
1Reaction
2Reference
2Substrates and Products (Substrate)
4Synonyms
1Systematic Name

Natural Substrates Products

Natural Substrates Products on EC 1.14.15.34 - 20-oxo-5-O-mycaminosyltylactone 23-monooxygenase

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NATURAL SUBSTRATE
NATURAL PRODUCT
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
REVERSIBILITY
r=reversible
ir=irreversible
?=not specified
20-oxo-5-O-beta-mycaminosyltylactone + 2 reduced ferredoxin [iron-sulfur] cluster + 2 H+ + O2
5-O-beta-mycaminosyltylonolide + 2 oxidized ferredoxin [iron-sulfur] cluster + H2O
show the reaction diagram
the enzyme is involved in the biosynthetic pathway of the macrolide antibiotic tylosin, which is produced by several species of Streptomyces
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