1.14.14.89: 4'-methoxyisoflavone 2'-hydroxylase

This is an abbreviated version!
For detailed information about 4'-methoxyisoflavone 2'-hydroxylase, go to the full flat file.

Reaction

Synonyms

daidzein and genistein reductase, dgr, EC 1.14.13.53, isoflavone 2'-hydroxylase, isoflavone 2'-monooxygenase, S-DGR

ECTree

1 Oxidoreductases

1.14 Acting on paired donors, with incorporation or reduction of molecular oxygen

1.14.14 With reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen into the other donor

1.14.14.89 4'-methoxyisoflavone 2'-hydroxylase

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Results	in table
4	Activating Compound
3	AA Sequence
1	CAS Registry Number
3	Cloned(Commentary)
3	Cofactor
9	Inhibitors
2	KM Value [mM]
5	Localization
1	Metals/Ions
7	Natural Substrates/ Products (Substrates)
7	Organism
5	Pathway
4	pH Optimum
1	Protein Variants
1	Reaction
4	Reaction Type
7	Reference
6	Source Tissue
1	Storage Stability
25	Substrates and Products (Substrate)
8	Synonyms
1	Systematic Name
3	Temperature Optimum [°C]

Inhibitors

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Inhibitors on EC 1.14.14.89 - 4'-methoxyisoflavone 2'-hydroxylase

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BAS 110

BAS 111

ratio CO:O2 of 9:1 leads to 88-96% inhibition

285320

cytochrome c

Cicer arietinum

0.01 mM cytochrome c reduces activity to 14%, 0.1 mM cytochrome c reduces activity to 4%

285318

juglone

Cicer arietinum

0.001 mM juglone reduces activity to 50%

ketoconazol

tetcyclasis

Triadimefone

additional information

Cicer arietinum

no inhibition by 5 mM KCN and 1 mM EDTA

285318