1.14.14.168: germacrene A acid 8beta-hydroxylase

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For detailed information about germacrene A acid 8beta-hydroxylase, go to the full flat file.

Reaction

Synonyms

CYP71BL1, CYP71BL6, GAA 8beta-hydroxylase, GAA 8x03-hydroxylase, HaG8H

ECTree

     1 Oxidoreductases

         1.14 Acting on paired donors, with incorporation or reduction of molecular oxygen

             1.14.14 With reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen into the other donor

                1.14.14.168 germacrene A acid 8beta-hydroxylase

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Results	in table
2	AA Sequence
3	Cloned(Commentary)
3	Cofactor
3	General Information
4	Natural Substrates/ Products (Substrates)
4	Organism
3	Pathway
1	pH Optimum
1	Purification (Commentary)
1	Reaction
4	Reference
4	Source Tissue
8	Substrates and Products (Substrate)
13	Synonyms
1	Systematic Name
1	Temperature Optimum [°C]

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Reference on EC 1.14.14.168 - germacrene A acid 8beta-hydroxylase

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REF.

AUTHORS

TITLE

JOURNAL

VOL.

PAGES

YEAR

ORGANISM (UNIPROT)

PUBMED ID

SOURCE

749465

Frey, M.; Schmauder, K.; Pateraki, I.; Spring, O.

Biosynthesis of eupatolide-A metabolic route for sesquiterpene lactone formation involving the P450 enzyme CYP71DD6

ACS Chem. Biol.

13

1536-1543

2018

Helianthus annuus (F8S1H3)

29758164

brenda

751031

Ikezawa, N.; Goepfert, J.C.; Nguyen, D.T.; Kim, S.U.; OMaille, P.E.; Spring, O.; Ro, D.K.

Lettuce costunolide synthase (CYP71BL2) and its homolog (CYP71BL1) from sunflower catalyze distinct regio- and stereoselective hydroxylations in sesquiterpene lactone metabolism

J. Biol. Chem.

286

21601-21611

2011

Helianthus annuus (F8S1H3), Helianthus annuus cv. HA300 (F8S1H3)

21515683

brenda

751862

Gou, J.; Hao, F.; Huang, C.; Kwon, M.; Chen, F.; Li, C.; Liu, C.; Ro, D.K.; Tang, H.; Zhang, Y.

Discovery of a non-stereoselective cytochrome P450 catalyzing either 8alpha- or 8beta-hydroxylation of germacrene A acid from the Chinese medicinal plant, Inula hupehensis

Plant J.

93

92-106

2018

Inula hupehensis

29086444

brenda

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