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1.14.14.168: germacrene A acid 8beta-hydroxylase

This is an abbreviated version!
For detailed information about germacrene A acid 8beta-hydroxylase, go to the full flat file.

Reaction

germacra-1(10),4,11(13)-trien-12-oate
+
[reduced NADPH-hemoprotein reductase]
+
O2
=
8beta-hydroxygermacra-1(10),4,11(13)-trien-12-oate
+
[oxidized NADPH-hemoprotein reductase]
+
H2O

Synonyms

CYP71BL1, CYP71BL6, GAA 8beta-hydroxylase, GAA 8x03-hydroxylase, HaG8H

ECTree

     1 Oxidoreductases
         1.14 Acting on paired donors, with incorporation or reduction of molecular oxygen
             1.14.14 With reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen into the other donor
                1.14.14.168 germacrene A acid 8beta-hydroxylase

Cloned

Cloned on EC 1.14.14.168 - germacrene A acid 8beta-hydroxylase

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CLONED (Commentary)
ORGANISM
UNIPROT
LITERATURE
coexpression of HaG8H with the enzyme combination HaGAS1 + HaGAO in Nicotiana benthamiana leaves results in the formation of the lactonized version inunolide
expression in yeast
-
sunflower HaG8H and LsCOS are coexpressed with Artemisia annua CPR in pESCUra vector