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1.14.14.161: nepetalactol monooxygenase

This is an abbreviated version!
For detailed information about nepetalactol monooxygenase, go to the full flat file.

Reaction

(+)-cis,trans-nepetalactol
+ 3 [reduced NADPH-hemoprotein reductase] + 3 O2 =
7-deoxyloganetate
+ 3 [oxidized NADPH-hemoprotein reductase] + 4 H2O

Synonyms

7-deoxyloganetic acid synthase, 7-deoxyloganic acid synthase, 7DLS, CYP76A26, iridoid oxidase

ECTree

     1 Oxidoreductases
         1.14 Acting on paired donors, with incorporation or reduction of molecular oxygen
             1.14.14 With reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen into the other donor
                1.14.14.161 nepetalactol monooxygenase

Reaction

Reaction on EC 1.14.14.161 - nepetalactol monooxygenase

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REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
(+)-cis,trans-nepetalactol + 3 [reduced NADPH-hemoprotein reductase] + 3 O2 = 7-deoxyloganetate + 3 [oxidized NADPH-hemoprotein reductase] + 4 H2O
show the reaction diagram
overall reaction
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(+)-cis,trans-nepetalactol + [reduced NADPH-hemoprotein reductase] + O2 = 7-deoxyloganetic alcohol + [oxidized NADPH-hemoprotein reductase] + H2O
show the reaction diagram
(1a)
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7-deoxyloganetic alcohol + [reduced NADPH-hemoprotein reductase] + O2 = iridotrial + [oxidized NADPH-hemoprotein reductase] + 2 H2O
show the reaction diagram
(1b)
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iridotrial + [reduced NADPH-hemoprotein reductase] + O2 = 7-deoxyloganetate + [oxidized NADPH-hemoprotein reductase] + H2O
show the reaction diagram
(1c)
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