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1.14.14.161: nepetalactol monooxygenase

This is an abbreviated version!
For detailed information about nepetalactol monooxygenase, go to the full flat file.

Reaction

(+)-cis,trans-nepetalactol
+ 3 [reduced NADPH-hemoprotein reductase] + 3 O2 =
7-deoxyloganetate
+ 3 [oxidized NADPH-hemoprotein reductase] + 4 H2O

Synonyms

7-deoxyloganetic acid synthase, 7-deoxyloganic acid synthase, 7DLS, CYP76A26, iridoid oxidase

ECTree

     1 Oxidoreductases
         1.14 Acting on paired donors, with incorporation or reduction of molecular oxygen
             1.14.14 With reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen into the other donor
                1.14.14.161 nepetalactol monooxygenase

Cloned

Cloned on EC 1.14.14.161 - nepetalactol monooxygenase

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CLONED (Commentary)
ORGANISM
UNIPROT
LITERATURE
expression in in Saccharomyces cerevisiae
expression of the gene in Saccharomyces cerevisiae confirms its function as an authentic 7-deoxyloganetic acid synthase that catalyzes the 3 step oxidation of iridodial-nepetalactol to form 7-deoxyloganetic acid