2.4.1.370: inositol phosphorylceramide mannosyltransferase

This is an abbreviated version!
For detailed information about inositol phosphorylceramide mannosyltransferase, go to the full flat file.

Reaction

Synonyms

BCL21, Csg1, Csg1p, CSH1, Csh1p, SUR1, YBR161w

ECTree

     2 Transferases

         2.4 Glycosyltransferases

             2.4.1 Hexosyltransferases

                2.4.1.370 inositol phosphorylceramide mannosyltransferase

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Results	in table
7	AA Sequence
5	Cloned(Commentary)
2	Expression
18	General Information
10	Localization
1	Metals/Ions
2	Natural Substrates/ Products (Substrates)
18	Organism
1	Pathway
1	pH Optimum
6	Posttranslational Modification
12	Protein Variants
1	Purification (Commentary)
1	Reaction
6	Reference
6	Substrates and Products (Substrate)
8	Subunits
24	Synonyms
1	Systematic Name

Systematic Name

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Systematic Name on EC 2.4.1.370 - inositol phosphorylceramide mannosyltransferase

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SYSTEMATIC NAME

IUBMB Comments

GDP-alpha-D-mannose:inositol phospho-(2'R)-2'-hydroxyphytoceramide mannosyltransferase

The simplest complex sphingolipid of yeast, inositol-phospho-alpha-hydroxyphytoceramide (IPC), is usually mannosylated to yield mannosyl-inositol-phospho-alpha hydroxyphytoceramide (MIPC). The enzyme is located in the Golgi apparatus, and utilizes GDP-mannose as the mannosyl group donor. It consists of a catalytic subunit (SUR1 or CSH1) and a regulatory subunit (CSG2).