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2.4.1.370: inositol phosphorylceramide mannosyltransferase

This is an abbreviated version!
For detailed information about inositol phosphorylceramide mannosyltransferase, go to the full flat file.

Word Map on EC 2.4.1.370

Reaction

GDP-alpha-D-mannose
+
a very-long-chain inositol phospho-(2'R)-2'-hydroxyphytoceramide
=
a very-long-chain mannosylinositol phospho-(2'R)-2'-hydroxyphytoceramide
+
GDP

Synonyms

BCL21, Csg1, Csg1p, CSH1, Csh1p, SUR1, YBR161w

ECTree

     2 Transferases
         2.4 Glycosyltransferases
             2.4.1 Hexosyltransferases
                2.4.1.370 inositol phosphorylceramide mannosyltransferase

Cloned

Cloned on EC 2.4.1.370 - inositol phosphorylceramide mannosyltransferase

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CLONED (Commentary)
ORGANISM
UNIPROT
LITERATURE
gene CGS1, sequence comparisons, recombinant expression of wild-type and mutant enzymes
gene CSG1, recombinant expression of C-terminally His6-myc-tagged enzyme in Saccharomyces cerevisiae. Association between recombinant HA3-tagged Csg2p and His6-myc-tagged Csg1p
gene CSH1, recombinant expression of C-terminally His6-myc-tagged enzyme in Saccharomyces cerevisiae
recombinant expression of FLAG3-tagged enzyme in Saccharomyces cerevisiae KA31-1A (CSG1 CSH1) cells resulting in SUY69 cells, coexpression of Cgs2 Ca2+-binding protein, quantitative real-time PCR enzyme expression analysis. Csg2 has an effect on the protein level of Csg1
recombinant FLAG3-tagged wild-type and mutant enzymes in Saccharomyces cerevisiae KA31-1A (CSG1 CSH1) cells resulting in SUY73 cells, coexpression of Cgs2 Ca2+-binding protein, quantitative real-time PCR enzyme expression analysis. Csg2 has an effect on the protein level of Csh1