2.3.1.287: phthioceranic/hydroxyphthioceranic acid synthase
This is an abbreviated version!
For detailed information about phthioceranic/hydroxyphthioceranic acid synthase, go to the full flat file.
Reaction
7 (S)-methylmalonyl-CoA + + 14 NADPH + 14 H+ = 7 CO2 + + 14 NADP+ + 7 CoA + 7 H2O
Synonyms
msl2, Pks2, polyketide synthase
ECTree
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General Information
General Information on EC 2.3.1.287 - phthioceranic/hydroxyphthioceranic acid synthase
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malfunction
metabolism
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a pks2 gene disruption mutant is incapable of producing hepta- and octamethyl phthioceranic acids and hydroxyphthioceranic acids that are the major acyl constituents of sulfolipids. Consequently, the pks2 mutant does not produce sulfolipids
malfunction
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strains with a disruption of the pks2 gene do not synthesize sulfolipids
malfunction
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strains with a disruption of the pks2 gene do not synthesize sulfolipids
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malfunction
-
a pks2 gene disruption mutant is incapable of producing hepta- and octamethyl phthioceranic acids and hydroxyphthioceranic acids that are the major acyl constituents of sulfolipids. Consequently, the pks2 mutant does not produce sulfolipids
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the enzyme is required for sulfolipid biosynthesis and synthesizes phthioceronic acids and hydroxyphthioceronic acids as the major components of mycobacterial sulfolipids
metabolism
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the enzyme synthesizes the methyl-branched fatty acyl components of sulfolipid-I
metabolism
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the enzyme synthesizes the methyl-branched fatty acyl components of sulfolipid-I
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