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2.1.1.335: 4-amino-anhydrotetracycline N4-methyltransferase

This is an abbreviated version!
For detailed information about 4-amino-anhydrotetracycline N4-methyltransferase, go to the full flat file.

Reaction

S-adenosyl-L-methionine
+
4-amino-4-de(dimethylamino)anhydrotetracycline
=
S-adenosyl-L-homocysteine
+
4-methylamino-4-de(dimethylamino)anhydrotetracycline

Synonyms

ctcO, oxyT

ECTree

     2 Transferases
         2.1 Transferring one-carbon groups
             2.1.1 Methyltransferases
                2.1.1.335 4-amino-anhydrotetracycline N4-methyltransferase

Systematic Name

Systematic Name on EC 2.1.1.335 - 4-amino-anhydrotetracycline N4-methyltransferase

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SYSTEMATIC NAME
IUBMB Comments
S-adenosyl-L-methionine:(4S,4aS,12aS)-4-amino-3,10,11,12a-tetrahydroxy-6-methyl-1,12-dioxo-4a,5-dihydro-4H-tetracene-2-carboxamide Nalpha-methyltransferase
The enzyme, characterized from the bacterium Streptomyces rimosus, participates in the biosynthesis of tetracycline antibiotics.