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2.1.1.335: 4-amino-anhydrotetracycline N4-methyltransferase

This is an abbreviated version!
For detailed information about 4-amino-anhydrotetracycline N4-methyltransferase, go to the full flat file.

Reaction

S-adenosyl-L-methionine
+
4-amino-4-de(dimethylamino)anhydrotetracycline
=
S-adenosyl-L-homocysteine
+
4-methylamino-4-de(dimethylamino)anhydrotetracycline

Synonyms

ctcO, oxyT

ECTree

     2 Transferases
         2.1 Transferring one-carbon groups
             2.1.1 Methyltransferases
                2.1.1.335 4-amino-anhydrotetracycline N4-methyltransferase

Reference

Reference on EC 2.1.1.335 - 4-amino-anhydrotetracycline N4-methyltransferase

Please use the Reference Search for a specific query.
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REF.
AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
Zhang, W.; Watanabe, K.; Cai, X.; Jung, M.; Tang, Y.; Zhan, J.
Identifying the minimal enzymes required for anhydrotetracycline biosynthesis
J. Am. Chem. Soc.
130
6068-6069
2008
Streptomyces rimosus (Q3S8P6)
Manually annotated by BRENDA team
Lukezic, T.; Fayad, A.; Bader, C.; Harmrolfs, K.; Bartuli, J.; Groß, S.; Lesnik, U.; Hennessen, F.; Herrmann, J.; Pikl, A.; Petkovic, H.; Müller, R.
Engineering atypical tetracycline formation in Amycolatopsis sulphurea for the production of modified chelocardin antibiotics
ACS Chem. Biol.
14
468-477
2019
Streptomyces rimosus (Q3S8P6)
Manually annotated by BRENDA team