EC Number   |
Protein Variants |
Reference |
|---|
   3.4.22.B50 | I353W |
the mutant exhibits about 10fold reduction in specificity toward ubiquitin compared to the wild type while the activity toward RLRGG-7-amido-4-methylcoumarin is essentially unaltered |
732827 |
| 3.4.22.B50 | I353R |
the mutant exhibits about 40fold reduction in specificity toward ubiquitin compared to the wild type while the activity toward RLRGG-7-amido-4-methylcoumarin is essentially unaltered |
732827 |
| 3.4.22.B50 | C1729A |
the mutant shows reduced interferon antagonistic activity compared to that of the wild type enzyme |
732257 |
| 3.4.22.B50 | T312A/I313V/I353R |
the mutant shows the greatest decrease in inhibitory activity in the interferon-beta promoter activity assay |
732827 |
| 3.4.22.B50 | S32T |
the mutation enhances the catalytic efficiency of the enzyme about 8fold while the thermostability of the mutant enzyme remains unchanged |
732725 |
| 3.4.22.B50 | A67Y |
the mutation enhances the catalytic efficiency of the enzyme about 8fold while the thermostability of the mutant enzyme remains unchanged. The specific activity against azo-casein is almost 2.4 times higher than wild type |
732725 |
| 3.4.22.B50 | S32T/A67Y |
the mutations enhance the catalytic efficiency of the enzyme about 8fold while the thermostability of the mutant enzyme remains unchanged |
732725 |
