C1729A
the mutant shows reduced interferon antagonistic activity compared to that of the wild type enzyme
porcine epidemic diarrhea virus
D1901A
the mutant almost completely loses interferon antagonistic activity compared to that of the wild type enzyme
porcine epidemic diarrhea virus
H1888A
the mutant almost completely loses interferon antagonistic activity compared to that of the wild type enzyme
porcine epidemic diarrhea virus
ubiquitin + H2O
porcine epidemic diarrhea virus
the enzyme processes both K-48 and K-63 linked polyubiquitin chains
?
?
ubiquitinated RIG-I + H2O
porcine epidemic diarrhea virus
deubiquitinated RIG-I + ubiquitin
?
ubiquitinated STING + H2O
porcine epidemic diarrhea virus
deubiquitinated STING + ubiquitin
?
ubiquitin + H2O
the enzyme processes both K-48 and K-63 linked polyubiquitin chains
732257
porcine epidemic diarrhea virus
?
?
ubiquitinated RIG-I + H2O
732257
porcine epidemic diarrhea virus
deubiquitinated RIG-I + ubiquitin
?
ubiquitinated STING + H2O
732257
porcine epidemic diarrhea virus
deubiquitinated STING + ubiquitin
?
C1729A
the mutant shows reduced interferon antagonistic activity compared to that of the wild type enzyme
porcine epidemic diarrhea virus
D1901A
the mutant almost completely loses interferon antagonistic activity compared to that of the wild type enzyme
porcine epidemic diarrhea virus
H1888A
the mutant almost completely loses interferon antagonistic activity compared to that of the wild type enzyme
porcine epidemic diarrhea virus
ubiquitin + H2O
porcine epidemic diarrhea virus
the enzyme processes both K-48 and K-63 linked polyubiquitin chains
?
?
ubiquitinated RIG-I + H2O
porcine epidemic diarrhea virus
deubiquitinated RIG-I + ubiquitin
?
ubiquitinated STING + H2O
porcine epidemic diarrhea virus
deubiquitinated STING + ubiquitin
?
ubiquitin + H2O
the enzyme processes both K-48 and K-63 linked polyubiquitin chains
732257
porcine epidemic diarrhea virus
?
?
ubiquitinated RIG-I + H2O
732257
porcine epidemic diarrhea virus
deubiquitinated RIG-I + ubiquitin
?
ubiquitinated STING + H2O
732257
porcine epidemic diarrhea virus
deubiquitinated STING + ubiquitin
?
752517
Chu
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porcine epidemic diarrhea virus
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1
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4
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1
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2
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1
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1
1
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2
2
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1
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3
1
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16
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1
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16
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1
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infectious bronchitis virus
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1
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1
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2
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1
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4
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754545
Mielech
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Severe acute respiratory syndrome-related coronavirus
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1
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Tabernaemontana divaricata
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1
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1
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3
1
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732827
van Kasteren
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Chaudhuri
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Wang
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Murine hepatitis virus
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Human coronavirus 229E
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Severe acute respiratory syndr ...
Alphacoronavirus, Alphacoronavirus SARS-CoV
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