EC Number |
Protein Variants |
Reference |
---|
3.4.22.B50 | C112S |
site-directed mutagenesis, the C112S mutant is monomeric, ubiquitin binding crystal structure analysis, overview |
731069 |
3.4.22.B50 | D165A |
site-directed mutagenesis, the mutant shows reduced activity in deubiquitination compared to the wild-type enzyme |
731069 |
3.4.22.B50 | E168A |
site-directed mutagenesis, the mutant shows reduced activity in deubiquitination compared to the wild-type enzyme |
731069 |
3.4.22.B50 | E168D |
site-directed mutagenesis, the mutant shows reduced activity in deubiquitination compared to the wild-type enzyme |
731069 |
3.4.22.B50 | E168R |
site-directed mutagenesis, the mutant shows reduced activity in deubiquitination compared to the wild-type enzyme |
731069 |
3.4.22.B50 | L163Q |
site-directed mutagenesis, the mutant shows reduced activity in deubiquitination compared to the wild-type enzyme |
731069 |
3.4.22.B50 | Y265A |
site-directed mutagenesis, the mutant shows reduced activity in deubiquitination compared to the wild-type enzyme |
731069 |
3.4.22.B50 | Y265F |
site-directed mutagenesis, the mutant shows reduced activity in deubiquitination compared to the wild-type enzyme |
731069 |
3.4.22.B50 | D1901A |
the mutant almost completely loses interferon antagonistic activity compared to that of the wild type enzyme |
732257 |
3.4.22.B50 | H1888A |
the mutant almost completely loses interferon antagonistic activity compared to that of the wild type enzyme |
732257 |