EC Number |
Recommended Name |
Source Tissue |
Reference |
---|
6.1.1.2 | tryptophan-tRNA ligase |
cerebral cortex |
about 0.2% of total soluble protein |
306 |
5.6.2.1 | DNA topoisomerase |
cerebral cortex |
neuron |
3800 |
4.1.2.13 | fructose-bisphosphate aldolase |
cerebral cortex |
isoenzyme III, IV, and V |
4948 |
3.4.17.22 | metallocarboxypeptidase D |
cerebral cortex |
- |
28967 |
3.1.1.2 | arylesterase |
cerebral cortex |
- |
35206 |
3.4.11.4 | tripeptide aminopeptidase |
cerebral cortex |
- |
35936 |
3.4.11.6 | aminopeptidase B |
cerebral cortex |
- |
35972, 682114 |
3.4.22.1 | cathepsin B |
cerebral cortex |
- |
36638 |
3.4.11.1 | leucyl aminopeptidase |
cerebral cortex |
- |
95178, 95227 |
3.1.3.9 | glucose-6-phosphatase |
cerebral cortex |
- |
134945 |
3.1.6.1 | arylsulfatase (type I) |
cerebral cortex |
activity increases gradually during development |
135532 |
3.6.1.13 | ADP-ribose diphosphatase |
cerebral cortex |
- |
209946, 655991 |
7.2.2.13 | Na+/K+-exchanging ATPase |
cerebral cortex |
- |
246958, 246966, 688017, 690001, 695408, 700430, 701165 |
1.1.1.188 | prostaglandin-F synthase |
cerebral cortex |
- |
389457 |
1.2.3.1 | aldehyde oxidase |
cerebral cortex |
- |
390422 |
1.6.99.1 | NADPH dehydrogenase |
cerebral cortex |
- |
392796 |
2.3.1.105 | alkylglycerophosphate 2-O-acetyltransferase |
cerebral cortex |
- |
486104, 486105 |
2.3.1.50 | serine C-palmitoyltransferase |
cerebral cortex |
- |
487177 |
2.3.1.61 | dihydrolipoyllysine-residue succinyltransferase |
cerebral cortex |
- |
487343 |
2.3.1.67 | 1-alkylglycerophosphocholine O-acetyltransferase |
cerebral cortex |
- |
487384, 487393 |
2.7.11.15 | beta-adrenergic-receptor kinase |
cerebral cortex |
- |
490911, 640698, 640709, 645000, 645003, 645005 |
2.7.11.15 | beta-adrenergic-receptor kinase |
cerebral cortex |
brain: highest beta-ARK mRNA concentrations in cerebral cortex and cerebellum |
490985 |
2.4.3.1 | beta-galactoside alpha-(2,6)-sialyltransferase |
cerebral cortex |
- |
637272 |
2.4.1.206 | lactosylceramide 1,3-N-acetyl-beta-D-glucosaminyltransferase |
cerebral cortex |
fetal |
638232, 638235 |
2.4.1.206 | lactosylceramide 1,3-N-acetyl-beta-D-glucosaminyltransferase |
cerebral cortex |
not adult |
638235 |
2.4.1.174 | glucuronylgalactosylproteoglycan 4-beta-N-acetylgalactosaminyltransferase |
cerebral cortex |
- |
638345 |
2.4.1.175 | glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase |
cerebral cortex |
- |
638345, 659262 |
3.4.23.45 | memapsin 1 |
cerebral cortex |
- |
638899, 638903 |
1.1.1.278 | 3beta-hydroxy-5alpha-steroid dehydrogenase |
cerebral cortex |
activity below detection limit of 0.1 fmol/mg protein/min |
639089 |
2.4.3.8 | alpha-N-acetylneuraminate alpha-2,8-sialyltransferase |
cerebral cortex |
- |
639661, 723273, 759644, 760219 |
2.7.1.107 | diacylglycerol kinase (ATP) |
cerebral cortex |
- |
640358, 640386 |
2.7.11.2 | [pyruvate dehydrogenase (acetyl-transferring)] kinase |
cerebral cortex |
- |
642132 |
3.4.22.52 | calpain-1 |
cerebral cortex |
- |
643998, 680913 |
1.17.1.4 | xanthine dehydrogenase |
cerebral cortex |
- |
644557, 644558 |
1.17.1.4 | xanthine dehydrogenase |
cerebral cortex |
high rate of dehydrogenase activity |
644557, 644558 |
1.21.99.3 | thyroxine 5-deiodinase |
cerebral cortex |
isozyme type III |
644796, 644798 |
2.7.11.15 | beta-adrenergic-receptor kinase |
cerebral cortex |
highest beta-ARK activity |
645001 |
2.7.8.11 | CDP-diacylglycerol-inositol 3-phosphatidyltransferase |
cerebral cortex |
- |
645316 |
3.1.2.2 | palmitoyl-CoA hydrolase |
cerebral cortex |
- |
646125, 646126, 646167 |
3.1.2.20 | acyl-CoA hydrolase |
cerebral cortex |
- |
646125, 646126, 646167 |
3.1.3.56 | inositol-polyphosphate 5-phosphatase |
cerebral cortex |
- |
646382 |
3.3.2.7 | hepoxilin-epoxide hydrolase |
cerebral cortex |
- |
647025 |
3.4.14.10 | tripeptidyl-peptidase II |
cerebral cortex |
- |
647148, 664475, 665981 |
3.1.4.11 | phosphoinositide phospholipase C |
cerebral cortex |
expression of PLC delta2 |
649088 |
3.1.1.23 | acylglycerol lipase |
cerebral cortex |
- |
650849, 653676 |
4.1.2.13 | fructose-bisphosphate aldolase |
cerebral cortex |
- |
651759 |
3.4.21.34 | plasma kallikrein |
cerebral cortex |
prekallikrein expression |
653115 |
3.1.2.2 | palmitoyl-CoA hydrolase |
cerebral cortex |
brain-specific isozyme |
653187 |
3.1.4.11 | phosphoinositide phospholipase C |
cerebral cortex |
- |
653348, 667504 |
3.1.1.4 | phospholipase A2 |
cerebral cortex |
- |
653367 |
1.1.1.153 | sepiapterin reductase (L-erythro-7,8-dihydrobiopterin forming) |
cerebral cortex |
pyramidal neurons |
655138 |
3.1.3.16 | protein-serine/threonine phosphatase |
cerebral cortex |
- |
655140, 682117 |
1.4.3.5 | pyridoxal 5'-phosphate synthase |
cerebral cortex |
25.9% of the activity in liver |
655483 |
1.3.99.5 | 3-oxo-5alpha-steroid 4-dehydrogenase (acceptor) |
cerebral cortex |
prefrontal, expression of isozymes 5alpha-R1 and 5alpha-R2 |
655526 |
1.2.1.12 | glyceraldehyde-3-phosphate dehydrogenase (phosphorylating) |
cerebral cortex |
- |
656594 |
3.4.17.21 | Glutamate carboxypeptidase II |
cerebral cortex |
cortical cells dissociated in cell culture |
656609 |
2.4.1.41 | polypeptide N-acetylgalactosaminyltransferase |
cerebral cortex |
- |
658240 |
1.6.1.2 | NAD(P)+ transhydrogenase (Re/Si-specific) |
cerebral cortex |
- |
658473 |
2.4.1.41 | polypeptide N-acetylgalactosaminyltransferase |
cerebral cortex |
enzyme form pp-GalNAc-T15 |
658739 |
1.4.3.13 | protein-lysine 6-oxidase |
cerebral cortex |
LOX on the surface of pyramidal cells in the grey matter, LOXL in the nuclei of cortex cells and in the cytosol of capillary endothelial cells |
659751 |
6.2.1.16 | acetoacetate-CoA ligase |
cerebral cortex |
in cerebral cortex expression of AACS mRNA is restricetd to neuronal cells |
661256 |
2.7.1.40 | pyruvate kinase |
cerebral cortex |
- |
661404, 661406 |
2.7.11.26 | tau-protein kinase |
cerebral cortex |
cold-water stress-induced tau phosphorylation pattern |
661724 |
2.4.1.214 | glycoprotein 3-alpha-L-fucosyltransferase |
cerebral cortex |
- |
661837 |
2.7.11.22 | cyclin-dependent kinase |
cerebral cortex |
- |
662124, 662688, 664179, 666467, 695204 |
2.7.11.26 | tau-protein kinase |
cerebral cortex |
- |
662124, 760847 |
2.7.11.1 | non-specific serine/threonine protein kinase |
cerebral cortex |
expression of CK1epsilon-3 |
662955 |
2.7.11.12 | cGMP-dependent protein kinase |
cerebral cortex |
predominant expression of isozyme cGKIbeta |
662962 |
5.1.1.18 | serine racemase |
cerebral cortex |
glial culture from |
663264 |
3.1.1.4 | phospholipase A2 |
cerebral cortex |
distribution of sPLa2-IIe, sPLA2-V, and sPLA2-X is mainly neuronal with highest abundance in cerebral cortex and hippocampus. Enzymes are differentially induced by kainic acid |
666137 |
3.1.4.3 | phospholipase C |
cerebral cortex |
synaptosomes |
666222 |
3.1.4.4 | phospholipase D |
cerebral cortex |
synaptosomes |
666222 |
3.4.19.12 | ubiquitinyl hydrolase 1 |
cerebral cortex |
- |
666444 |
3.4.19.12 | ubiquitinyl hydrolase 1 |
cerebral cortex |
down-regulation of UCHL-1 mRNA and protein in dementia with Lewy bodies, either in pure forms not associated with Alzheimer disease, and in common forms, with accompanying Alzheimer disease changes, but not in Parkinson disease. UCHL-3 expression reduced in Parkinson disease and dementia with Lewy bodies |
666444 |
3.1.4.4 | phospholipase D |
cerebral cortex |
PLD2 expression is observed in the marginal zone from the earliest stage and then declines and completely disappears by embryonic day 20 |
666455 |
3.4.22.62 | caspase-9 |
cerebral cortex |
of newborn piglets |
666456 |
3.4.22.62 | caspase-9 |
cerebral cortex |
of newborn piglet |
666462 |
3.4.24.56 | insulysin |
cerebral cortex |
isolated brain microvessels, in patients with Alzheimers disease with cerebral amyloid angiopathy enzyme protein level is up to 44% increased, but enzyme activity is significantly reduced |
667412 |
3.4.17.1 | carboxypeptidase A |
cerebral cortex |
- |
667459, 668122 |
3.4.17.15 | carboxypeptidase A2 |
cerebral cortex |
- |
667459 |
3.4.21.B42 | hippostasin |
cerebral cortex |
expression revealed by immunohistochemistry |
667873 |
3.4.17.23 | angiotensin-converting enzyme 2 |
cerebral cortex |
about 10% of the ACE2 gene expression in kidney cortex |
668896 |
3.6.1.28 | thiamine-triphosphatase |
cerebral cortex |
- |
668963 |
3.6.1.5 | apyrase |
cerebral cortex |
increase in enzymic activity from birth to day 30, decrease afterwards, highest enzymic activity at day 30, highest affinity for enzyme at day 365, relative abundance of enzyme is highest at day 15 of ontogeny |
668983 |
3.1.4.11 | phosphoinositide phospholipase C |
cerebral cortex |
PLCeta2 is restricted to brain. PLCeta2 gradually increases during brain development. PLCeta2 is not detected in embryos. At 1 week after birth PLCeta2 is barely detected and expression is first observed at weeks after birth |
669369 |
3.4.11.3 | cystinyl aminopeptidase |
cerebral cortex |
- |
669637 |
3.4.21.93 | Proprotein convertase 1 |
cerebral cortex |
- |
669904 |
5.6.1.2 | dynein ATPase |
cerebral cortex |
- |
669959 |
3.5.1.2 | glutaminase |
cerebral cortex |
isozymes LGA and KGA |
670391 |
3.1.4.17 | 3',5'-cyclic-nucleotide phosphodiesterase |
cerebral cortex |
external layer of |
670448 |
3.4.24.B10 | ADAM12 endopeptidase |
cerebral cortex |
fetal |
670683 |
1.6.99.1 | NADPH dehydrogenase |
cerebral cortex |
distribution of NADPH-diaphorase activity in different human cortical areas, remarkable laminar and interareal differences across areas |
672837 |
1.1.1.178 | 3-hydroxy-2-methylbutyryl-CoA dehydrogenase |
cerebral cortex |
- |
673530 |
2.6.1.42 | branched-chain-amino-acid transaminase |
cerebral cortex |
- |
673846 |
1.2.1.105 | 2-oxoglutarate dehydrogenase system |
cerebral cortex |
- |
673870, 762740 |
5.6.1.1 | microtubule-severing ATPase |
cerebral cortex |
- |
675537, 699690 |
2.7.11.17 | Ca2+/calmodulin-dependent protein kinase |
cerebral cortex |
isozymes CaMKIdelta and CaMKIalpha |
676188 |
2.7.1.20 | adenosine kinase |
cerebral cortex |
- |
676193 |
3.1.6.1 | arylsulfatase (type I) |
cerebral cortex |
no significant changes in enzyme level upon feeding ethanol-containing Lieber-DeCarli liquid diet |
677433 |
3.1.6.8 | cerebroside-sulfatase |
cerebral cortex |
- |
677433 |